Lineage for d3n84b_ (3n84 B:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2530460Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices
  4. 2530461Superfamily d.93.1: SH2 domain [55550] (2 families) (S)
  5. 2530462Family d.93.1.1: SH2 domain [55551] (35 proteins)
    Pfam PF00017
  6. 2530616Protein Growth factor receptor-bound protein 2 (GRB2) [55563] (1 species)
  7. 2530617Species Human (Homo sapiens) [TaxId:9606] [55564] (38 PDB entries)
  8. 2530632Domain d3n84b_: 3n84 B: [182012]
    Other proteins in same PDB: d3n84e2
    automated match to d1fhsa_
    complexed with cl, gol, mg

Details for d3n84b_

PDB Entry: 3n84 (more details), 2 Å

PDB Description: Crystal Structure of the Grb2 SH2 Domain in Complex with a 23-Membered Macrocyclic Ligand Having the Sequence pYVNVP
PDB Compounds: (B:) Growth factor receptor-bound protein 2

SCOPe Domain Sequences for d3n84b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3n84b_ d.93.1.1 (B:) Growth factor receptor-bound protein 2 (GRB2) {Human (Homo sapiens) [TaxId: 9606]}
emkphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrd
gagkyflwvvkfnslnelvdyhrstsvsrnqqiflrdieqvpqqpt

SCOPe Domain Coordinates for d3n84b_:

Click to download the PDB-style file with coordinates for d3n84b_.
(The format of our PDB-style files is described here.)

Timeline for d3n84b_: