Lineage for d3kmxa_ (3kmx A:)
- Root: SCOPe 2.04
Class b: All beta proteins [48724] (176 folds) 
Fold b.50: Acid proteases [50629] (1 superfamily)
barrel, closed; n=6, S=10, complex topologySuperfamily b.50.1: Acid proteases [50630] (4 families) 
Family b.50.1.2: Pepsin-like [50646] (11 proteins)
duplication: consists of two similar barrel domains
N-terminal: barrel, partly opened; n*=6, S*=10
Protein beta-secretase (memapsin) [50671] (1 species) Species Human (Homo sapiens) [TaxId:9606] [50672] (242 PDB entries)
Uniprot P56817 58-446 ! Uniprot P56817 60-447
Domain d3kmxa_: 3kmx A: [179461]
automated match to d1fkna_
complexed with g00
Details for d3kmxa_
PDB Entry: 3kmx (more details), 1.7 Å
PDB Description: structure of bace bound to sch346572
PDB Compounds: (A:) Beta-secretase 1SCOPe Domain Sequences for d3kmxa_:
Sequence; same for both SEQRES and ATOM records: (download)
>d3kmxa_ b.50.1.2 (A:) beta-secretase (memapsin) {Human (Homo sapiens) [TaxId: 9606]}
epgrrgsfvemvdnlrgksgqgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhry
yqrqlsstyrdlrkgvyvpytqgkwegelgtdlvsiphgpnvtvraniaaitesdkffin
gsnwegilglayaeiarpddslepffdslvkqthvpnlfslqlcgagfplnqsevlasvg
gsmiiggidhslytgslwytpirrewyyeviivrveingqdlkmdckeynydksivdsgt
tnlrlpkkvfeaavksikaasstekfpdgfwlgeqlvcwqagttpwnifpvislylmgev
tnqsfritilpqqylrpvedvatsqddcykfaisqsstgtvmgavimegfyvvfdrarkr
igfavsachvhdefrtaavegpfvtldmedcgyni
SCOPe Domain Coordinates for d3kmxa_:
Click to download the PDB-style file with coordinates for d3kmxa_.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d3kmxa_:
- d3kmxa_ first appeared in SCOPe 2.01
- d3kmxa_ appears in SCOPe 2.03
- d3kmxa_ appears in SCOPe 2.05
- d3kmxa_ appears in the current release, SCOPe 2.08
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