Lineage for d3k74a_ (3k74 A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2903429Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2903430Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2903431Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 2903517Protein Dihydrofolate reductase, prokaryotic type [53599] (9 species)
  7. 2903520Species Escherichia coli K-12 [TaxId:83333] [187149] (11 PDB entries)
  8. 2903529Domain d3k74a_: 3k74 A: [179137]
    Other proteins in same PDB: d3k74b_
    automated match to d1ddra_

Details for d3k74a_

PDB Entry: 3k74 (more details), 1.95 Å

PDB Description: disruption of protein dynamics by an allosteric effector antibody
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d3k74a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3k74a_ c.71.1.1 (A:) Dihydrofolate reductase, prokaryotic type {Escherichia coli K-12 [TaxId: 83333]}
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr

SCOPe Domain Coordinates for d3k74a_:

Click to download the PDB-style file with coordinates for d3k74a_.
(The format of our PDB-style files is described here.)

Timeline for d3k74a_:

View in 3D
Domains from other chains:
(mouse over for more information)
d3k74b_