Lineage for d2x2ma_ (2x2m A:)
- Root: SCOPe 2.05
Class d: Alpha and beta proteins (a+b) [53931] (381 folds) 
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helicalSuperfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) 
shares functional and structural similarities with the ATP-grasp fold and PIPKFamily d.144.1.0: automated matches [191359] (1 protein)
not a true familyProtein automated matches [190417] (21 species)
not a true proteinSpecies Human (Homo sapiens) [TaxId:9606] [187294] (615 PDB entries) 
Domain d2x2ma_: 2x2m A: [169829]
automated match to d1agwb_
complexed with fmt, x2m
Details for d2x2ma_
PDB Entry: 2x2m (more details), 2.5 Å
PDB Description: crystal structure of phosphorylated ret tyrosine kinase domain with inhibitor
PDB Compounds: (A:) proto-oncogene tyrosine-protein kinase receptor retSCOPe Domain Sequences for d2x2ma_:
Sequence, based on SEQRES records: (download)
>d2x2ma_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gplslsvdafkiledpkwefprknlvlgktlgegefgkvvkatafhlkgragyttvavkm
lkenaspselrdllsefnvlkqvnhphviklygacsqdgpllliveyakygslrgflres
rkvgpgylgsggsrnsssldhpderaltmgdlisfawqisqgmqylaemklvhrdlaarn
ilvaegrkmkisdfglsrdvyeedsyvkrsqgripvkwmaieslfdhiyttqsdvwsfgv
llweivtlggnpypgipperlfnllktghrmerpdncseemyrlmlqcwkqepdkrpvfa
diskdlekmmvkrr
Sequence, based on observed residues (ATOM records): (download)
>d2x2ma_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gplslsvdafkildpkwefprknlvlgktlgefgkvvkatafhlkgragyttvavkmlke
naspselrdllsefnvlkqvnhphviklygacsqdgpllliveyakygslrgflresral
tmgdlisfawqisqgmqylaemklvhrdlaarnilvaegrkmkisdfglsrdvyeedsyv
krsqgripvkwmaieslfdhiyttqsdvwsfgvllweivtlggnpypgipperlfnllkt
ghrmerpdncseemyrlmlqcwkqepdkrpvfadiskdlekmmvkrr
SCOPe Domain Coordinates for d2x2ma_:
Click to download the PDB-style file with coordinates for d2x2ma_.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d2x2ma_:
- d2x2ma_ first appeared in SCOPe 2.01
- d2x2ma_ appears in SCOPe 2.04
- d2x2ma_ is called d2x2ma1 in SCOPe 2.06
- d2x2ma_ appears in the current release, SCOPe 2.08, called d2x2ma1
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