Lineage for d2wl0a_ (2wl0 A:)

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2067626Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2067627Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2067628Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2068913Protein automated matches [190433] (11 species)
    not a true protein
  7. 2069023Species Human immunodeficiency virus type 1 (z2/cdc-z34 isolate) [TaxId:11683] [189175] (1 PDB entry)
  8. 2069024Domain d2wl0a_: 2wl0 A: [169427]
    automated match to d1k6ca_
    complexed with 5ah

Details for d2wl0a_

PDB Entry: 2wl0 (more details), 1.9 Å

PDB Description: hiv-1 protease inhibitors containing a tertiary alcohol in the transition-state mimic with improved cell-based antiviral activity
PDB Compounds: (A:) Protease

SCOPe Domain Sequences for d2wl0a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2wl0a_ b.50.1.1 (A:) automated matches {Human immunodeficiency virus type 1 (z2/cdc-z34 isolate) [TaxId: 11683]}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qipieicghkaigtvlvgptptnvigrnlltqigctlnf

SCOPe Domain Coordinates for d2wl0a_:

Click to download the PDB-style file with coordinates for d2wl0a_.
(The format of our PDB-style files is described here.)

Timeline for d2wl0a_: