Lineage for d2shpa3 (2shp A:111-218)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2571840Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices
  4. 2571841Superfamily d.93.1: SH2 domain [55550] (2 families) (S)
  5. 2571842Family d.93.1.1: SH2 domain [55551] (35 proteins)
    Pfam PF00017
  6. 2572259Protein Tyrosine phoshatase shp-2 [55589] (1 species)
  7. 2572260Species Human (Homo sapiens) [TaxId:9606] [55590] (1 PDB entry)
  8. 2572262Domain d2shpa3: 2shp A:111-218 [40534]
    Other proteins in same PDB: d2shpa1, d2shpb1
    complexed with cat

Details for d2shpa3

PDB Entry: 2shp (more details), 2 Å

PDB Description: tyrosine phosphatase shp-2
PDB Compounds: (A:) shp-2

SCOPe Domain Sequences for d2shpa3:

Sequence, based on SEQRES records: (download)

>d2shpa3 d.93.1.1 (A:111-218) Tyrosine phoshatase shp-2 {Human (Homo sapiens) [TaxId: 9606]}
rwfhghlsgkeaeklltekgkhgsflvresqshpgdfvlsvrtgddkgesndgkskvthv
mircqelkydvgggerfdsltdlvehykknpmvetlgtvlqlkqplnt

Sequence, based on observed residues (ATOM records): (download)

>d2shpa3 d.93.1.1 (A:111-218) Tyrosine phoshatase shp-2 {Human (Homo sapiens) [TaxId: 9606]}
rwfhghlsgkeaeklltekgkhgsflvresqshpgdfvlsvrtgdndgkskvthvmircq
elkydvgggerfdsltdlvehykknpmvetlgtvlqlkqplnt

SCOPe Domain Coordinates for d2shpa3:

Click to download the PDB-style file with coordinates for d2shpa3.
(The format of our PDB-style files is described here.)

Timeline for d2shpa3: