Lineage for d2cu0a1 (2cu0 A:3-96,A:207-480)
- Root: SCOPe 2.06
Class c: Alpha and beta proteins (a/b) [51349] (148 folds) Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites
Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families) 
The phosphate moiety of substrate binds in the 'common' phosphate-binding site
Family c.1.5.1: Inosine monophosphate dehydrogenase (IMPDH) [51413] (1 protein) Protein Inosine monophosphate dehydrogenase (IMPDH) [51414] (8 species) 
Species Pyrococcus horikoshii [TaxId:53953] [159379] (1 PDB entry)
Uniprot O58045 3-96,207-480
Domain d2cu0a1: 2cu0 A:3-96,A:207-480 [146425]
disordered CBS domain is cut out
complexed with xmp
Details for d2cu0a1
PDB Entry: 2cu0 (more details), 2.1 Å
PDB Description: Crystal structure of inosine-5'-monophosphate dehydrogenase from Pyrococcus horikoshii OT3
PDB Compounds: (A:) inosine-5'-monophosphate dehydrogenaseSCOPe Domain Sequences for d2cu0a1:
Sequence, based on SEQRES records: (download)
>d2cu0a1 c.1.5.1 (A:3-96,A:207-480) Inosine monophosphate dehydrogenase (IMPDH) {Pyrococcus horikoshii [TaxId: 53953]}
kfveklekaikgytfddvllipqatevepkdvdvstritpnvklnipilsaamdtvtewe
mavamaregglgvihrnmgieeqveqvkrvkraeXkyknavrdengellvaaavspfdik
raieldkagvdvivvdtahahnlkaiksmkemrqkvdadfivgnianpkavddltfadav
kvgigpgsicttrivagvgvpqitavamvadraqeyglyviadggirysgdivkaiaaga
davmlgnllagtkeapgkeviingrkykqyrgmgslgammkggaeryyqggymktrkfvp
egvegvvpyrgtvsevlyqlvgglkagmgyvgarnirelkekgefviithagikeshphd
iiitneapn
Sequence, based on observed residues (ATOM records): (download)
>d2cu0a1 c.1.5.1 (A:3-96,A:207-480) Inosine monophosphate dehydrogenase (IMPDH) {Pyrococcus horikoshii [TaxId: 53953]}
kfveklekaikgytfddvllipqatevepkdvdvstritpnvklnipilsaamdtvtewe
mavamaregglgvihrnmgieeqveqvkrvkraeXkyknavrdengellvaaavspfdik
raieldkagvdvivvdtahahnlkaiksmkemrqkvdadfivgnianpkavddltfadav
kvgigpgsicttrivagvgvpqitavamvadraqeyglyviadggirysgdivkaiaaga
davmlgnllagtkeapgkeviingrkykqyrgmgslgammkymktrkfvpegvegvvpyr
gtvsevlyqlvgglkagmgyvgarnirelkekgefviithagikeshphdiiitneapn
SCOPe Domain Coordinates for d2cu0a1:
Click to download the PDB-style file with coordinates for d2cu0a1.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d2cu0a1:
- d2cu0a1 first appeared in SCOP 1.75
- d2cu0a1 appears in SCOPe 2.05
- d2cu0a1 appears in SCOPe 2.07
- d2cu0a1 appears in the current release, SCOPe 2.08
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