Lineage for d2afma1 (2afm A:33-361)
- Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds) 
Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loopsSuperfamily c.56.5: Zn-dependent exopeptidases [53187] (10 families) 
core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
Family c.56.5.8: Glutaminyl-peptide cyclotransferase-like [142532] (1 protein)
part of Pfam PF04389Protein Glutaminyl-peptide cyclotransferase, QPCT [142533] (2 species)
Glutaminyl cyclaseSpecies Human (Homo sapiens) [TaxId:9606] [142534] (29 PDB entries)
Uniprot Q16769 33-361
Domain d2afma1: 2afm A:33-361 [126698]
complexed with so4, zn
Details for d2afma1
PDB Entry: 2afm (more details), 1.66 Å
PDB Description: Crystal structure of human glutaminyl cyclase at pH 6.5
PDB Compounds: (A:) Glutaminyl-peptide cyclotransferaseSCOPe Domain Sequences for d2afma1:
Sequence, based on SEQRES records: (download)
>d2afma1 c.56.5.8 (A:33-361) Glutaminyl-peptide cyclotransferase, QPCT {Human (Homo sapiens) [TaxId: 9606]}
asawpeeknyhqpailnssalrqiaegtsisemwqndlqpllierypgspgsyaarqhim
qriqrlqadwvleidtflsqtpygyrsfsniistlnptakrhlvlachydskyfshwnnr
vfvgatdsavpcammlelaraldkkllslktvsdskpdlslqliffdgeeaflhwspqds
lygsrhlaakmastphppgargtsqlhgmdllvlldligapnptfpnffpnsarwferlq
aiehelhelgllkdhslegryfqnysyggviqddhipflrrgvpvlhlipspfpevwhtm
ddneenldestidnlnkilqvfvleylhl
Sequence, based on observed residues (ATOM records): (download)
>d2afma1 c.56.5.8 (A:33-361) Glutaminyl-peptide cyclotransferase, QPCT {Human (Homo sapiens) [TaxId: 9606]}
asawpeeknyhqpailnssalrqiaegtsisemwqndlqpllierypgspgsyaarqhim
qriqrlqadwvleidtflsqtpygyrsfsniistlnptakrhlvlachydskyfshwnnr
vfvgatdsavpcammlelaraldkkllslkpdlslqliffdgeeaflhwspqdslygsrh
laakmastphppgargtsqlhgmdllvlldligapnptfpnffpnsarwferlqaiehel
helgllkdhslegryfqnysyggviqddhipflrrgvpvlhlipspfpevwhtmddneen
ldestidnlnkilqvfvleylhl
SCOPe Domain Coordinates for d2afma1:
Click to download the PDB-style file with coordinates for d2afma1.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d2afma1:
- d2afma1 first appeared in SCOP 1.73
- d2afma1 appears in SCOPe 2.07
View in 3D
