Lineage for d2a65a1 (2a65 A:5-513)

  1. Root: SCOPe 2.06
  2. 2250849Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)
  3. 2256405Fold f.54: SNF-like [161069] (1 superfamily)
    12 transmembrane helices; duplication: consists of two structurally similar halves
  4. 2256406Superfamily f.54.1: SNF-like [161070] (1 family) (S)
  5. 2256407Family f.54.1.1: SNF-like [161071] (2 proteins)
    Pfam PF00209; Sodium:neurotransmitter symporter
  6. 2256408Protein Na(+):neurotransmitter symporter homologue LeuT [161072] (1 species)
  7. 2256409Species Aquifex aeolicus [TaxId:63363] [161073] (38 PDB entries)
    Uniprot O67854 5-513
  8. 2256410Domain d2a65a1: 2a65 A:5-513 [146040]
    Other proteins in same PDB: d2a65a2
    complexed with bog, cl, leu, na

Details for d2a65a1

PDB Entry: 2a65 (more details), 1.65 Å

PDB Description: crystal structure of leutaa, a bacterial homolog of na+/cl--dependent neurotransmitter transporters
PDB Compounds: (A:) Na(+):neurotransmitter symporter (Snf family)

SCOPe Domain Sequences for d2a65a1:

Sequence, based on SEQRES records: (download)

>d2a65a1 f.54.1.1 (A:5-513) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsili
rgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvw
iaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaava
ffgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmi
afledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiff
wifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvw
itrfyiiglflfltflvflaerrrnhesa

Sequence, based on observed residues (ATOM records): (download)

>d2a65a1 f.54.1.1 (A:5-513) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
rehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiewa
mgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikflv
glvpeppptdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirg
iskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwia
avgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaff
gvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmiaf
ledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwi
fgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwit
rfyiiglflfltflvflaerrrnhesa

SCOPe Domain Coordinates for d2a65a1:

Click to download the PDB-style file with coordinates for d2a65a1.
(The format of our PDB-style files is described here.)

Timeline for d2a65a1:

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d2a65a2