Lineage for d1xm6a_ (1xm6 A:)
- Root: SCOPe 2.06
Class a: All alpha proteins [46456] (289 folds) 
Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
multihelical; consists of two different alpha-helical bundlesSuperfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) 
Family a.211.1.2: PDEase [48548] (7 proteins)
Pfam PF00233; multihelical; can be divided into three subdomains
Protein Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b [48549] (1 species) Species Human (Homo sapiens) [TaxId:9606] [48550] (30 PDB entries)
Uniprot Q07343 324-667
Domain d1xm6a_: 1xm6 A: [115471]
complexed with 5rm, mg, zn
Details for d1xm6a_
PDB Entry: 1xm6 (more details), 1.92 Å
PDB Description: Catalytic Domain Of Human Phosphodiesterase 4B In Complex With (R)-Mesopram
PDB Compounds: (A:) cAMP-specific 3',5'-cyclic phosphodiesterase 4BSCOPe Domain Sequences for d1xm6a_:
Sequence, based on SEQRES records: (download)
>d1xm6a_ a.211.1.2 (A:) Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b {Human (Homo sapiens) [TaxId: 9606]}
edhlakeledlnkwglnifnvagyshnrpltcimyaifqerdllktfrissdtfitymmt
ledhyhsdvayhnslhaadvaqsthvllstpaldavftdleilaaifaaaihdvdhpgvs
nqflintnselalmyndesvlenhhlavgfkllqeehcdifmnltkkqrqtlrkmvidmv
latdmskhmslladlktmvetkkvtssgvllldnytdriqvlrnmvhcadlsnptkslel
yrqwtdrimeeffqqgdkerergmeispmcdkhtasveksqvgfidyivhplwetwadlv
qpdaqdildtlednrnwyqsmipqspsppldeqnrdcqglmekfqfeltld
Sequence, based on observed residues (ATOM records): (download)
>d1xm6a_ a.211.1.2 (A:) Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b {Human (Homo sapiens) [TaxId: 9606]}
edhlakeledlnkwglnifnvagyshnrpltcimyaifqerdllktfrissdtfitymmt
ledhyhsdvayhnslhaadvaqsthvllstpaldavftdleilaaifaaaihdvdhpgvs
nqflintnselalmyndesvlenhhlavgfkllqeehcdifmnltkkqrqtlrkmvidmv
latdmskhmslladlktmvetkkvtssgvllldnytdriqvlrnmvhcadlsnptkslel
yrqwtdrimeeffqqgdkerergmeispmcdkhtasveksqvgfidyivhplwetwadlv
qpdaqdildtlednrnwyqsmipcqglmekfqfeltld
SCOPe Domain Coordinates for d1xm6a_:
Click to download the PDB-style file with coordinates for d1xm6a_.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d1xm6a_:
- d1xm6a_ first appeared in SCOP 1.71
- d1xm6a_ appears in SCOPe 2.05
- d1xm6a_ appears in SCOPe 2.07
- d1xm6a_ appears in the current release, SCOPe 2.08
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