SCOPe 2.04: Domain d1qzfa2: 1qzf A:181-521

Lineage for d1qzfa2 (1qzf A:181-521)

Root: SCOPe 2.04
Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
contains large mixed beta-sheet
Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
automatically mapped to Pfam PF00303
Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)
Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain [55841] (2 species)
Species Cryptosporidium hominis [TaxId:237895] [100887] (3 PDB entries)
Domain d1qzfa2: 1qzf A:181-521 [96634]
Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
complexed with cb3, fol, ndp, ump

Details for d1qzfa2

PDB Entry: 1qzf (more details), 2.8 Å

PDB Description: Crystal structure of DHFR-TS from Cryptosporidium hominis

PDB Compounds: (A:) Bifunctional dihydrofolate reductase-thymidylate synthase

SCOPe Domain Sequences for d1qzfa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1qzfa2 d.117.1.1 (A:181-521) Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain {Cryptosporidium hominis [TaxId: 237895]}
ktlqncdpargqlksiddtvdllgeifgirkmgnrhkfpkeeiyntpsirfgrehyefqy
ldllsrvlengayrenrtgistysifgqmmrfdmresfpllttkkvairsifeeliwfik
gdtngnhliekkvyiwsgngskeyleriglghreendlgpiygfqwrhyngeyktmhddy
tgvgvdqlaklietlknnpkdrrhiltawnpsalsqmalppchvlsqyyvtndnclscnl
yqrscdlglgspfniasyailtmmlaqvcgyepgelaifigdahiyenhltqlkeqlsrt
prpfpqlkfkrkveniedfkwedieligyypyptikmdmav

SCOPe Domain Coordinates for d1qzfa2:

Click to download the PDB-style file with coordinates for d1qzfa2.
(The format of our PDB-style files is described here.)

Timeline for d1qzfa2: