Lineage for d1osfa_ (1osf A:)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 732553Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
    8-stranded mixed beta-sheet; 2 layers: alpha/beta
  4. 732554Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (4 families) (S)
  5. 732555Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (1 protein)
  6. 732556Protein HSP90 [55876] (3 species)
  7. 732609Species Human (Homo sapiens) [TaxId:9606] [55878] (35 PDB entries)
  8. 732615Domain d1osfa_: 1osf A: [87380]
    complexed with acy, kos, mpd

Details for d1osfa_

PDB Entry: 1osf (more details), 1.75 Å

PDB Description: Human Hsp90 in complex with 17-desmethoxy-17-N,N-Dimethylaminoethylamino-Geldanamycin
PDB Compounds: (A:) heat shock 90kDa protein 1, alpha; heat shock 90kD protein 1, alpha

SCOP Domain Sequences for d1osfa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1osfa_ d.122.1.1 (A:) HSP90 {Human (Homo sapiens) [TaxId: 9606]}
dqpmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdps
kldsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadi
smigqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvil
hlkedqteyleerrikeivkkhsqfigypitlfve

SCOP Domain Coordinates for d1osfa_:

Click to download the PDB-style file with coordinates for d1osfa_.
(The format of our PDB-style files is described here.)

Timeline for d1osfa_: