Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds) |
Fold e.8: DNA/RNA polymerases [56671] (1 superfamily) divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members |
Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families) "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain |
Family e.8.1.3: T7 RNA polymerase [56691] (2 proteins) |
Protein T7 RNA polymerase [56692] (1 species) multidomain; mostly alpha |
Species Bacteriophage T7 [TaxId:10760] [56693] (11 PDB entries) |
Domain d1mswd_: 1msw D: [79427] elongation complex; shows dramatic conformational changes in the transition from initiation to elongation transcription protein/DNA complex; protein/RNA complex |
PDB Entry: 1msw (more details), 2.1 Å
SCOPe Domain Sequences for d1mswd_:
Sequence, based on SEQRES records: (download)
>d1mswd_ e.8.1.3 (D:) T7 RNA polymerase {Bacteriophage T7 [TaxId: 10760]} ntiniakndfsdielaaipfntladhygerlareqlalehesyemgearfrkmferqlka gevadnaaakplittllpkmiarindwfeevkakrgkrptafqflqeikpeavayitikt tlacltsadnttvqavasaigraiedearfgrirdleakhfkknveeqlnkrvghvykka fmqvveadmlskgllggeawsswhkedsihvgvrciemliestgmvslhrqnagvvgqds etielapeyaeaiatragalagispmfqpcvvppkpwtgitgggywangrrplalvrths kkalmryedvympevykainiaqntawkinkkvlavanvitkwkhcpvedipaiereelp mkpedidmnpealtawkraaaavyrkdkarksrrislefmleqankfanhkaiwfpynmd wrgrvyavsmfnpqgndmtkglltlakgkpigkegyywlkihgancagvdkvpfperikf ieenhenimacaksplentwwaeqdspfcflafcfeyagvqhhglsyncslplafdgscs giqhfsamlrdevggravnllpsetvqdiygivakkvneilqadaingtdnevvtvtden tgeisekvklgtkalagqwlaygvtrsvtkrsvmtlaygskefgfrqqvledtiqpaids gkglmftqpnqaagymakliwesvsvtvvaaveamnwlksaakllaaevkdkktgeilrk rcavhwvtpdgfpvwqeykkpiqtrlnlmflgqfrlqptintnkdseidahkqesgiapn fvhsqdgshlrktvvwahekygiesfalihdsfgtipadaanlfkavretmvdtyescdv ladfydqfadqlhesqldkmpalpakgnlnlrdilesdfafa
>d1mswd_ e.8.1.3 (D:) T7 RNA polymerase {Bacteriophage T7 [TaxId: 10760]} ntiniakndfsdielaaipfntladhygerlareqlalehesyemgearfrkmferqlka gevadnaaakplittllpkmiarindwfeevkakrgkrptafqflqeikpeavayitikt tlacltsadnttvqavasaigraiedearfgrirdleakhfkknveeqlnkrvghvykka fmqvveadmlskgllggeawsswhkedsihvgvrciemliestgmvslhrqsetielape yaeaiatragalagispmfqpcvvppkpwtgitgggywangrrplalvrthskkalmrye dvympevykainiaqntawkinkkvlavanvitkwkhcpvedipaiereelpmktawkra aaavyrkdkarksrrislefmleqankfanhkaiwfpynmdwrgrvyavsmfnpqgndmt kglltlakgkpigkegyywlkihgancagvdkvpfperikfieenhenimacaksplent wwaeqdspfcflafcfeyagvqhhglsyncslplafdgscsgiqhfsamlrdevggravn llpsetvqdiygivakkvneilqadaingtdnevvtvtdentgeisekvklgtkalagqw laygvtrsvtkrsvmtlaygskefgfrqqvledtiqpaidsgkglmftqpnqaagymakl iwesvsvtvvaaveamnwlksaakllaaevkdkktgeilrkrcavhwvtpdgfpvwqeyk kpiqtrlnlmflgqfrlqptintnkdseidahkqesgiapnfvhsqdgshlrktvvwahe kygiesfalihdsfgtipadaanlfkavretmvdtyescdvladfydqfadqlhesqldk mpalpakgnlnlrdilesdfafa
Timeline for d1mswd_: