Class b: All beta proteins [48724] (178 folds) |
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
Superfamily b.1.1: Immunoglobulin [48726] (5 families) |
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins) |
Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species) VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species |
Species Mouse (Mus musculus), cluster 2 [TaxId:10090] [88526] (28 PDB entries) |
Domain d1moea1: 1moe A:1-119 [85030] Other proteins in same PDB: d1moea2, d1moeb2 part of anti-CEA scFv T84.66; VL to VH linkage: includes linker residues 112-119; assembles as a diabody complexed with so4 |
PDB Entry: 1moe (more details), 2.6 Å
SCOPe Domain Sequences for d1moea1:
Sequence; same for both SEQRES and ATOM records: (download)
>d1moea1 b.1.1.1 (A:1-119) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 2 [TaxId: 10090]} divltqspaslavslgqratmscragesvdifgvgflhwyqqkpgqppklliyrasnles gipvrfsgtgsrtdftliidpveaddvatyycqqtnedpytfgggtkleikgggsgggg
Timeline for d1moea1: