Lineage for d1m48b_ (1m48 B:)
- Root: SCOPe 2.08
Class a: All alpha proteins [46456] (290 folds) 
Fold a.26: 4-helical cytokines [47265] (1 superfamily)
core: 4 helices; bundle, closed; left-handed twist; 2 crossover connectionsSuperfamily a.26.1: 4-helical cytokines [47266] (4 families) 
there are two different topoisomers of this fold with different entanglements of the two crossover connections
Family a.26.1.2: Short-chain cytokines [47286] (14 proteins) 
Protein Interleukin-2 (IL-2) [47301] (1 species) Species Human (Homo sapiens) [TaxId:9606] [47302] (20 PDB entries) 
Domain d1m48b_: 1m48 B: [74444]
complexed with frg
Details for d1m48b_
PDB Entry: 1m48 (more details), 1.95 Å
PDB Description: crystal structure of human il-2 complexed with (r)-n-[2-[1- (aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l- phenylalanine methyl ester
PDB Compounds: (B:) interleukin-2SCOPe Domain Sequences for d1m48b_:
Sequence, based on SEQRES records: (download)
>d1m48b_ a.26.1.2 (B:) Interleukin-2 (IL-2) {Human (Homo sapiens) [TaxId: 9606]}
ssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeel
kpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnrwit
fcqsiistlt
Sequence, based on observed residues (ATOM records): (download)
>d1m48b_ a.26.1.2 (B:) Interleukin-2 (IL-2) {Human (Homo sapiens) [TaxId: 9606]}
ssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeel
kpleevlnlaqsknfrdlisninvivlelkgsettfmceyadetativeflnrwitfcqs
iistlt
SCOPe Domain Coordinates for d1m48b_:
Click to download the PDB-style file with coordinates for d1m48b_.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d1m48b_:
- d1m48b_ first appeared in SCOP 1.61
- d1m48b_ appears in SCOPe 2.07
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