Lineage for d1irl__ (1irl -)

  1. Root: SCOP 1.71
  2. 530466Class a: All alpha proteins [46456] (226 folds)
  3. 536620Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 536621Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 536689Family a.26.1.2: Short-chain cytokines [47286] (11 proteins)
  6. 536712Protein Interleukin-2 (IL-2) [47301] (1 species)
  7. 536713Species Human (Homo sapiens) [TaxId:9606] [47302] (11 PDB entries)
  8. 536732Domain d1irl__: 1irl - [16883]
    mutant

Details for d1irl__

PDB Entry: 1irl (more details)

PDB Description: the solution structure of the f42a mutant of human interleukin 2

SCOP Domain Sequences for d1irl__:

Sequence; same for both SEQRES and ATOM records: (download)

>d1irl__ a.26.1.2 (-) Interleukin-2 (IL-2) {Human (Homo sapiens)}
aptssstkktqlqlehllldlqmilnginnyknpkltrmltakfympkkatelkhlqcle
eelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistlt

SCOP Domain Coordinates for d1irl__:

Click to download the PDB-style file with coordinates for d1irl__.
(The format of our PDB-style files is described here.)

Timeline for d1irl__: