Lineage for d1i4eb_ (1i4e B:)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 691281Fold c.17: Caspase-like [52128] (1 superfamily)
    3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest
  4. 691282Superfamily c.17.1: Caspase-like [52129] (2 families) (S)
    mature protein may be composed of two chains folded in a single domain
  5. 691283Family c.17.1.1: Caspase catalytic domain [52130] (7 proteins)
  6. 691337Protein Caspase-8 [52135] (1 species)
  7. 691338Species Human (Homo sapiens) [TaxId:9606] [52136] (5 PDB entries)
  8. 691354Domain d1i4eb_: 1i4e B: [61686]
    Other proteins in same PDB: d1i4ea_
    complexed to p35
    complexed with ace

Details for d1i4eb_

PDB Entry: 1i4e (more details), 3 Å

PDB Description: crystal structure of the caspase-8/p35 complex
PDB Compounds: (B:) caspase-8

SCOP Domain Sequences for d1i4eb_:

Sequence, based on SEQRES records: (download)

>d1i4eb_ c.17.1.1 (B:) Caspase-8 {Human (Homo sapiens) [TaxId: 9606]}
ldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfei
kphhdctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqft
glkcpslagkpkvffiqacqgdnyqkgipvetdseeqpylemdlsspqtryipdeadfll
gmatvnncvsyrnpaegtwyiqslcqslrercprgddiltiltevnyevsnkddkknmgk
qmpqptftlrkklvfpsd

Sequence, based on observed residues (ATOM records): (download)

>d1i4eb_ c.17.1.1 (B:) Caspase-8 {Human (Homo sapiens) [TaxId: 9606]}
ldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfei
kphhdctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqft
glkcpslagkpkvffiqacqgdnyqkgipvetdtryipdeadfllgmatvnncvsyrnpa
egtwyiqslcqslrercprgddiltiltevnyevsnkddkknmgkqmpqptftlrkklvf
psd

SCOP Domain Coordinates for d1i4eb_:

Click to download the PDB-style file with coordinates for d1i4eb_.
(The format of our PDB-style files is described here.)

Timeline for d1i4eb_:

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Domains from other chains:
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d1i4ea_