PDB entry 8e6c

View 8e6c on RCSB PDB site
Description: Crystal structure of MERS 3CL protease in complex with a m-fluorophenyl dimethyl sulfane inhibitor
Class: HYDROLASE, Viral protein/Inhibitor
Keywords: PROTEASE, protease Inhhibitors, HYDROLASE, Viral protein-Inhibitor complex
Deposited on 2022-08-22, released 2022-09-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-09-07, with a file datestamp of 2022-09-02.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Orf1a protein
    Species: Middle East respiratory syndrome-related coronavirus [TaxId:1335626]
    Gene: ORF1a
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d8e6ca1, d8e6ca2
  • Heterogens: UTU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >8e6cA (A:)
mhhhhhhsglvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadqlsdpn
ydallismtnhsfsvqkhigapanlrvvghamqgtllkltvdvanpstpaytfttvkpga
afsvlacyngrptgtftvvmrpnytikgsflcgscgsvgytkegsvinfcymhqmelang
thtgsafdgtmygafmdkqvhqvqltdkycsvnvvawlyaailngcawfvkpnrtsvvsf
newalanqftefvgtqsvdmlavktgvaieqllyaiqqlytgfqgkqilgstmledeftp
edvnmqimgvvmq

    Sequence, based on observed residues (ATOM records): (download) 
    >8e6cA (A:)
hhsglvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadqlsdpnydall
ismtnhsfsvqkhanlrvvghamqgtllkltvdvanpstpaytfttvkpgaafsvlacyn
grptgtftvvmrpnytikgsflcgscgsvgytkegsvinfcymhqmelangthtgsafdg
tmygafmdkqvhqvqltdkycsvnvvawlyaailngcawfvkpnrtsvvsfnewalanqf
tefvgtqsvdmlavktgvaieqllyaiqqlytgfqgkqilgstmledeftpedvnmqimg
vv