PDB entry 8ddz

View 8ddz on RCSB PDB site
Description: TEM-1 beta-lactamase A237Y
Class: hydrolase
Keywords: Hydrolase, Beta-lactamase
Deposited on 2022-06-19, released 2022-09-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-09-07, with a file datestamp of 2022-09-02.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase TEM
    Species: Escherichia coli [TaxId:562]
    Gene: blaTEM-1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62593 (1-263)
      • expression tag (0)
      • engineered mutation (157)
      • engineered mutation (212)
    Domains in SCOPe 2.08: d8ddza_
  • Chain 'B':
    Compound: Beta-lactamase TEM
    Species: Escherichia coli [TaxId:562]
    Gene: blaTEM-1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62593 (1-263)
      • expression tag (0)
      • engineered mutation (157)
      • engineered mutation (212)
    Domains in SCOPe 2.08: d8ddzb_
  • Chain 'C':
    Compound: Beta-lactamase TEM
    Species: Escherichia coli [TaxId:562]
    Gene: blaTEM-1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62593 (1-263)
      • expression tag (0)
      • engineered mutation (157)
      • engineered mutation (212)
    Domains in SCOPe 2.08: d8ddzc_
  • Chain 'D':
    Compound: Beta-lactamase TEM
    Species: Escherichia coli [TaxId:562]
    Gene: blaTEM-1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62593 (1-263)
      • expression tag (0)
      • engineered mutation (157)
      • engineered mutation (212)
    Domains in SCOPe 2.08: d8ddzd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >8ddzA (A:)
ghpetlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrv
dagqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttigg
pkeltaflhnmgdhvtrldrwepelneaipnderdtttpaamattlrklltgelltlasr
qqlidwmeadkvagpllrsalpagwfiadksgygergsrgiiaalgpdgkpsrivviytt
gsqatmdernrqiaeigaslikhw

    Sequence, based on observed residues (ATOM records): (download) 
    >8ddzA (A:)
petlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrvda
gqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttiggpk
eltaflhnmgdhvtrldrwepelneaipnderdtttpaamattlrklltgelltlasrqq
lidwmeadkvagpllrsalpagwfiadksgygergsrgiiaalgpdgkpsrivviyttgs
qatmdernrqiaeigaslikhw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >8ddzB (B:)
ghpetlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrv
dagqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttigg
pkeltaflhnmgdhvtrldrwepelneaipnderdtttpaamattlrklltgelltlasr
qqlidwmeadkvagpllrsalpagwfiadksgygergsrgiiaalgpdgkpsrivviytt
gsqatmdernrqiaeigaslikhw

    Sequence, based on observed residues (ATOM records): (download) 
    >8ddzB (B:)
petlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrvda
gqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttiggpk
eltaflhnmgdhvtrldrwepelneaipnderdtttpaamattlrklltgelltlasrqq
lidwmeadkvagpllrsalpagwfiadksgygergsrgiiaalgpdgkpsrivviyttgs
qatmdernrqiaeigaslikhw

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >8ddzC (C:)
ghpetlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrv
dagqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttigg
pkeltaflhnmgdhvtrldrwepelneaipnderdtttpaamattlrklltgelltlasr
qqlidwmeadkvagpllrsalpagwfiadksgygergsrgiiaalgpdgkpsrivviytt
gsqatmdernrqiaeigaslikhw

    Sequence, based on observed residues (ATOM records): (download) 
    >8ddzC (C:)
petlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrvda
gqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttiggpk
eltaflhnmgdhvtrldrwepelneaipnderdtttpaamattlrklltgelltlasrqq
lidwmeadkvagpllrsalpagwfiadksgygergsrgiiaalgpdgkpsrivviyttgs
qatmdernrqiaeigaslikhw

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >8ddzD (D:)
ghpetlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrv
dagqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttigg
pkeltaflhnmgdhvtrldrwepelneaipnderdtttpaamattlrklltgelltlasr
qqlidwmeadkvagpllrsalpagwfiadksgygergsrgiiaalgpdgkpsrivviytt
gsqatmdernrqiaeigaslikhw

    Sequence, based on observed residues (ATOM records): (download) 
    >8ddzD (D:)
petlvkvkdaedqlgarvgyieldlnsgkilesfrpeerfpmmstfkvllcgavlsrvda
gqeqlgrrihysqndlveyspvtekhltdgmtvrelcsaaitmsdntaanlllttiggpk
eltaflhnmgdhvtrldrwepelneaipnderdtttpaamattlrklltgelltlasrqq
lidwmeadkvagpllrsalpagwfiadksgygergsrgiiaalgpdgkpsrivviyttgs
qatmdernrqiaeigaslikhw