PDB entry 8d4s

View 8d4s on RCSB PDB site
Description: Crystal Structure of Cathepsin G Inhibited by Eap1 from S. aureus
Class: protein binding
Keywords: Protease Inhibitor, Immune Evasion, Neutrophil, S. aureus, PROTEIN BINDING
Deposited on 2022-06-02, released 2022-12-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-12-21, with a file datestamp of 2022-12-16.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cathepsin G, C-terminal truncated form
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d8d4sa_
  • Chain 'B':
    Compound: Extracellular Adherence Protein
    Species: Staphylococcus aureus subsp. aureus Mu50 [TaxId:158878]
    Gene: map, SAV1938
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99QS1 (3-99)
      • expression tag (0-2)
  • Chain 'C':
    Compound: Cathepsin G, C-terminal truncated form
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d8d4sc_
  • Chain 'D':
    Compound: Extracellular Adherence Protein
    Species: Staphylococcus aureus subsp. aureus Mu50 [TaxId:158878]
    Gene: map, SAV1938
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99QS1 (3-99)
      • expression tag (0-2)
  • Chain 'E':
    Compound: Cathepsin G, C-terminal truncated form
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d8d4se_
  • Chain 'F':
    Compound: Extracellular Adherence Protein
    Species: Staphylococcus aureus subsp. aureus Mu50 [TaxId:158878]
    Gene: map, SAV1938
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99QS1 (3-99)
      • expression tag (0-2)
  • Chain 'G':
    Compound: Cathepsin G, C-terminal truncated form
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d8d4sg_
  • Chain 'H':
    Compound: Extracellular Adherence Protein
    Species: Staphylococcus aureus subsp. aureus Mu50 [TaxId:158878]
    Gene: map, SAV1938
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99QS1 (3-99)
      • expression tag (0-2)
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >8d4sA (A:)
    iiggresrphsrpymaylqiqspagqsrcggflvredfvltaahcwgsninvtlgahniq
    rrentqqhitarrairhpqynqrtiqndimllqlsrrvrrnrnvnpvalpraqeglrpgt
    lctvagwgrvsmrrgtdtlrevqlrvqrdrqclrifgsydprrqicvgdrrerkaafkgd
    sggpllcnnvahgivsygkssgvppevftrvssflpwirttmr
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >8d4sC (C:)
    iiggresrphsrpymaylqiqspagqsrcggflvredfvltaahcwgsninvtlgahniq
    rrentqqhitarrairhpqynqrtiqndimllqlsrrvrrnrnvnpvalpraqeglrpgt
    lctvagwgrvsmrrgtdtlrevqlrvqrdrqclrifgsydprrqicvgdrrerkaafkgd
    sggpllcnnvahgivsygkssgvppevftrvssflpwirttmr
    

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >8d4sE (E:)
    iiggresrphsrpymaylqiqspagqsrcggflvredfvltaahcwgsninvtlgahniq
    rrentqqhitarrairhpqynqrtiqndimllqlsrrvrrnrnvnpvalpraqeglrpgt
    lctvagwgrvsmrrgtdtlrevqlrvqrdrqclrifgsydprrqicvgdrrerkaafkgd
    sggpllcnnvahgivsygkssgvppevftrvssflpwirttmr
    

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download)
    >8d4sG (G:)
    iiggresrphsrpymaylqiqspagqsrcggflvredfvltaahcwgsninvtlgahniq
    rrentqqhitarrairhpqynqrtiqndimllqlsrrvrrnrnvnpvalpraqeglrpgt
    lctvagwgrvsmrrgtdtlrevqlrvqrdrqclrifgsydprrqicvgdrrerkaafkgd
    sggpllcnnvahgivsygkssgvppevftrvssflpwirttmr
    

  • Chain 'H':
    No sequence available.