PDB entry 8bio

View 8bio on RCSB PDB site
Description: Crystal structure of human Ephrin type-A receptor 2 (EPHA2) Kinase domain in complex with MRAL5
Class: transferase
Keywords: EPHA2, ECK, Typ I Inhibitor, TRANSFERASE
Deposited on 2022-11-02, released 2022-11-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-11-23, with a file datestamp of 2022-11-18.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ephrin type-A receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHA2, ECK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29317 (1-305)
      • expression tag (0)
    Domains in SCOPe 2.08: d8bioa_
  • Heterogens: QRD, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >8bioA (A:)
gdpnqavlkftteihpscvtrqkvigagefgevykgmlktssgkkevpvaiktlkagyte
kqrvdflgeagimgqfshhniirlegviskykpmmiiteymengaldkflrekdgefsvl
qlvgmlrgiaagmkylanmnyvhrdlaarnilvnsnlvckvsdfglsrvleddpeatytt
sggkipirwtapeaisyrkftsasdvwsfgivmwevmtygerpywelsnhevmkaindgf
rlptpmdcpsaiyqlmmqcwqqerarrpkfadivsildklirapdslktladfdprvsir
lpstsg

    Sequence, based on observed residues (ATOM records): (download) 
    >8bioA (A:)
tteihpscvtrqkviggevykgmlkevpvaiktlkagytekqrvdflgeagimgqfshhn
iirlegviskykpmmiiteymengaldkflrekdgefsvlqlvgmlrgiaagmkylanmn
yvhrdlaarnilvnsnlvckvsdfglsrvleddpegkipirwtapeaisyrkftsasdvw
sfgivmwevmtygerpywelsnhevmkaindgfrlptpmdcpsaiyqlmmqcwqqerarr
pkfadivsildklirapdslktladfdprvsir