PDB entry 8a4b

View 8a4b on RCSB PDB site
Description: Structure of human Rep15:Rab3B_Q81L complex.
Class: endocytosis
Keywords: Rab GTPase, Effector, ENDOCYTOSIS
Deposited on 2022-06-10, released 2022-08-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-08-10, with a file datestamp of 2022-08-05.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Rab15 effector protein
    Species: Homo sapiens [TaxId:9606]
    Gene: REP15
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6BDI9 (3-222)
      • expression tag (0-2)
      • variant (87)
  • Chain 'B':
    Compound: Ras-related protein Rab-3B
    Species: Homo sapiens [TaxId:9606]
    Gene: RAB3B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20337 (1-173)
      • initiating methionine (0)
      • engineered mutation (64)
    Domains in SCOPe 2.08: d8a4bb_
  • Chain 'C':
    Compound: Rab15 effector protein
    Species: Homo sapiens [TaxId:9606]
    Gene: REP15
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6BDI9 (3-222)
      • expression tag (0-2)
      • variant (87)
  • Chain 'D':
    Compound: Ras-related protein Rab-3B
    Species: Homo sapiens [TaxId:9606]
    Gene: RAB3B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20337 (1-173)
      • initiating methionine (0)
      • engineered mutation (64)
    Domains in SCOPe 2.08: d8a4bd_
  • Heterogens: GTP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >8a4bB (B:)
mnfdymfklliignssvgktsflfryaddtftpafvstvgidfkvktvyrhekrvklqiw
dtagleryrtittayyrgamgfilmyditneesfnavqdwatqiktyswdnaqvilvgnk
cdmeeervvptekgqllaeqlgfdffeasakenisvrqaferlvdaicdkmsds

    Sequence, based on observed residues (ATOM records): (download) 
    >8a4bB (B:)
nfdymfklliignssvgktsflfryaddtftpafvstvgidfkvktvyrhekrvklqiwd
tagleryrtittayyrgamgfilmyditneesfnavqdwatqiktyswdnaqvilvgnkc
dmeeervvptekgqllaeqlgfdffeasakenisvrqaferlvdaicdkm

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >8a4bD (D:)
mnfdymfklliignssvgktsflfryaddtftpafvstvgidfkvktvyrhekrvklqiw
dtagleryrtittayyrgamgfilmyditneesfnavqdwatqiktyswdnaqvilvgnk
cdmeeervvptekgqllaeqlgfdffeasakenisvrqaferlvdaicdkmsds

    Sequence, based on observed residues (ATOM records): (download) 
    >8a4bD (D:)
fdymfklliignssvgktsflfryaddtftpafvstvgidfkvktvyrhekrvklqiwdt
agleryrtittayyrgamgfilmyditneesfnavqdwatqiktyswdnaqvilvgnkcd
meeervvptekgqllaeqlgfdffeasakenisvrqaferlvdaicdkm