PDB entry 8a3q

View 8a3q on RCSB PDB site
Description: Human Plasma Kallekrein in complex with 14W
Class: hydrolase
Keywords: Inhibitor, Complex, serine-like protease, HYDROLASE
Deposited on 2022-06-08, released 2022-11-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-11-09, with a file datestamp of 2022-11-04.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Plasma kallikrein
    Species: Homo sapiens [TaxId:9606]
    Gene: KLKB1, KLK3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03952 (0-262)
      • engineered mutation (7)
      • engineered mutation (127)
    Domains in SCOPe 2.08: d8a3qa_
  • Heterogens: UNL, MES, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >8a3qA (A:)
    ntgdnsvsttktstrivggtnsswgewpwqvslqvkltaqrhlcggslighqwvltaahc
    fdglplqdvwriysgilnlsditkdtpfsqikeiiihqnykvsegnhdialiklqaplny
    tefqkpislpskgdtstiytncwvtgwgfskekgeiqnilqkvniplvtneecqkryqdy
    kitqrmvcagykeggkdackgdsggplvckhngmwrlvgitswgegcarreqpgvytkva
    eymdwilektqssdgkaqmqspa
    

    Sequence, based on observed residues (ATOM records): (download)
    >8a3qA (A:)
    ivggtnsswgewpwqvslqvkltaqrhlcggslighqwvltaahcfdglplqdvwriysg
    ilnlsditkdtpfsqikeiiihqnykvsegnhdialiklqaplnytefqkpislpskgdt
    stiytncwvtgwgfskekgeiqnilqkvniplvtneecqkryqdykitqrmvcagykegg
    kdackgdsggplvckhngmwrlvgitswgegcarreqpgvytkvaeymdwilektqssdg
    k