PDB entry 7zkz

View 7zkz on RCSB PDB site
Description: Crystal structure of cystinosin from Arabidopsis thaliana bound to two nanobodies
Class: membrane protein
Keywords: Cystinosin; PQ-loop protein; proton coupling; cystine transport, MEMBRANE PROTEIN
Deposited on 2022-04-13, released 2022-08-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-08-31, with a file datestamp of 2022-08-26.
Experiment type: XRAY
Resolution: 2.33 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cystinosin homolog
    Species: Arabidopsis thaliana [TaxId:3702]
    Gene: At5g40670, MNF13.23
    Database cross-references and differences (RAF-indexed):
    • Uniprot P57758 (0-269)
      • expression tag (270-276)
  • Chain 'B':
    Compound: Llama nanobody
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 7ZKZ (0-127)
    Domains in SCOPe 2.08: d7zkzb_
  • Chain 'C':
    Compound: Nanobody
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 7ZKZ (0-122)
    Domains in SCOPe 2.08: d7zkzc_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7zkzB (B:)
qvqlvesggglvqaggslrlscaasgrtitpistyvmgwfrqdpgkerefvasiswngan
tyyadsvkgrftisrdnakntvylqmnslkpedtavyycaadpeshvrlrlgvgaywgrg
tqvtvssa

    Sequence, based on observed residues (ATOM records): (download) 
    >7zkzB (B:)
qvqlvesggglvqaggslrlscaasgrtitpistyvmgwfrqdpgkerefvasiswngan
tyyadsvkgrftisrdnakntvylqmnslkpedtavyycaadpeshvrlrlgvgaywgrg
tqvtvss

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7zkzC (C:)
qvqlvesgggsaqpggslrlscavsgsvselntmgwfrqapgkqrelvaritatsdatny
adsvkgrftisrdngwntvylqsnslkpedsavyycnvegapswfsgirsywgqgtqvtv
ssa

    Sequence, based on observed residues (ATOM records): (download) 
    >7zkzC (C:)
qvqlvesgggsaqpggslrlscavsgsvselntmgwfrqapgkqrelvaritatsdatny
adsvkgrftisrdngwntvylqsnslkpedsavyycnvegapswfsgirsywgqgtqvtv
ss