PDB entry 7wmc

View 7wmc on RCSB PDB site
Description: Crystal structure of macrocyclic peptide 1 bound to human Nicotinamide N-methyltransferase
Class: transferase
Keywords: Nicotinamide N-methyltransferase, TRANSFERASE
Deposited on 2022-01-14, released 2022-08-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-08-31, with a file datestamp of 2022-08-26.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nicotinamide N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: Nnmt
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40261 (1-258)
      • expression tag (0)
      • conflict (101)
    Domains in SCOPe 2.08: d7wmca_
  • Chain 'B':
    Compound: Nicotinamide N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: Nnmt
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40261 (1-258)
      • expression tag (0)
      • conflict (101)
    Domains in SCOPe 2.08: d7wmcb_
  • Chain 'C':
    Compound: peptide1
    Species: unidentified [TaxId:32644]
    Database cross-references and differences (RAF-indexed):
    • PDB 7WMC (0-9)
  • Chain 'D':
    Compound: peptide1
    Species: unidentified [TaxId:32644]
    Database cross-references and differences (RAF-indexed):
    • PDB 7WMC (0-9)
  • Chain 'E':
    Compound: peptide1
    Species: unidentified [TaxId:32644]
    Database cross-references and differences (RAF-indexed):
    • PDB 7WMC
  • Heterogens: XA6, 2IQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7wmcA (A:)
gsgftskdtylshfnprdylekyykfgsrhsaesqilkhllknlfkifcldgvkgdllid
igsgptiyqllsacesfkeivvtdysdqnlqelekwlkkepaafdwspvvtyvcdlegnr
vkgpekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlptycralr
nlgsllkpggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfevisqs
ysstmanneglfslvarkl

    Sequence, based on observed residues (ATOM records): (download) 
    >7wmcA (A:)
gftskdtylshfnprdylekyykfgsrhsaesqilkhllknlfkifcldgvkgdllidig
sgptiyqllsacesfkeivvtdysdqnlqelekwlkkepaafdwspvvtyvcdlegnrvk
gpekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlptycralrnl
gsllkpggflvimdalgreaveaavkeagytiewfeviglfslvarkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7wmcB (B:)
gsgftskdtylshfnprdylekyykfgsrhsaesqilkhllknlfkifcldgvkgdllid
igsgptiyqllsacesfkeivvtdysdqnlqelekwlkkepaafdwspvvtyvcdlegnr
vkgpekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlptycralr
nlgsllkpggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfevisqs
ysstmanneglfslvarkl

    Sequence, based on observed residues (ATOM records): (download) 
    >7wmcB (B:)
gftskdtylshfnprdylekyykfgsrhsaesqilkhllknlfkifcldgvkgdllidig
sgptiyqllsacesfkeivvtdysdqnlqelekwlkkepaafdwspvvtyvcdlegnrvk
gpekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlptycralrnl
gsllkpggflvimdallgreaveaavkeagytiewfevieglfslvarkl

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.