PDB entry 7t5z

View 7t5z on RCSB PDB site
Description: P. aeruginosa LpxA in complex with ligand L8
Class: transferase
Keywords: Lpxa, lipid A, LPS, lipopolysaccharide, UDP-N-acetylglucosamine O-acyltransferase, TRANSFERASE
Deposited on 2021-12-13, released 2022-07-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-07-06, with a file datestamp of 2022-07-01.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa PA7 [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7t5za_
  • Chain 'B':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa PA7 [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7t5zb_
  • Chain 'C':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa PA7 [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7t5zc_
  • Chain 'D':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa PA7 [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7t5zd_
  • Chain 'E':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa PA7 [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7t5ze_
  • Chain 'F':
    Compound: acyl-[acyl-carrier-protein]--udp-n-acetylglucosamine o-acyltransferase
    Species: Pseudomonas aeruginosa PA7 [TaxId:381754]
    Gene: lpxA, PSPA7_1495
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7t5zf_
  • Heterogens: F6I, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7t5zA (A:)
mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
evavfrdsiqsatrgitr

    Sequence, based on observed residues (ATOM records): (download) 
    >7t5zA (A:)
slidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqf
ssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahigh
dsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayv
tvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpe
vavfrdsiqsatrgitr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7t5zB (B:)
mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
evavfrdsiqsatrgitr

    Sequence, based on observed residues (ATOM records): (download) 
    >7t5zB (B:)
slidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqf
ssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahigh
dsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayv
tvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpe
vavfrdsiqsatrgitr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7t5zC (C:)
mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
evavfrdsiqsatrgitr

    Sequence, based on observed residues (ATOM records): (download) 
    >7t5zC (C:)
lidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqfs
svgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahighd
svignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayvt
vfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpev
avfrdsiqsatrgitr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7t5zD (D:)
mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
evavfrdsiqsatrgitr

    Sequence, based on observed residues (ATOM records): (download) 
    >7t5zD (D:)
slidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqf
ssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahigh
dsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayv
tvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpe
vavfrdsiqsatrgitr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7t5zE (E:)
mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
evavfrdsiqsatrgitr

    Sequence, based on observed residues (ATOM records): (download) 
    >7t5zE (E:)
slidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqf
ssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahigh
dsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayv
tvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpe
vavfrdsiqsatrgitr

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7t5zF (F:)
mslidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyq
fssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahig
hdsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpay
vtvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfp
evavfrdsiqsatrgitr

    Sequence, based on observed residues (ATOM records): (download) 
    >7t5zF (F:)
slidpraiidpsarlaadvqvgpwsivgaeveigegtvigphvvlkgptkigkhnriyqf
ssvgedtpdlkykgeptrlvigdhnviregvtihrgtvqdraettigdhnlimayahigh
dsvignhcilvnntalaghvhvddwailsgytlvhqycrigahsfsgmgsaigkdvpayv
tvfgnpaearsmnfegmrrrgfsseaihalrraykvvyrqghtveealaelaesaaqfpe
vavfrdsiqsatrgitr