PDB entry 7s6v

View 7s6v on RCSB PDB site
Description: Leishmania infantum Glycogen Synthase Kinase 3 beta bound to CGP60474
Class: transferase/inhibitor
Keywords: Protein kinase, inhibitor, TRANSFERASE, GSK3s, GSK3beta, Leishmania infantum, TRANSFERASE-INHIBITOR complex
Deposited on 2021-09-15, released 2022-11-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-11-09, with a file datestamp of 2022-11-04.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen Synthase Kinase 3
    Species: Leishmania infantum [TaxId:5671]
    Gene: GSK3, LINF_180007700, LINJ_18_0270
    Database cross-references and differences (RAF-indexed):
    • Uniprot A4HXQ3 (1-355)
      • expression tag (0)
    Domains in SCOPe 2.08: d7s6va_
  • Heterogens: 8II, EDO, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7s6vA (A:)
smslnaadaadersrkemdrfqvermagqgtfgtvqlgkekstgmsvaikkviqdprfrn
relqimqdlavlhhpnivqlqsyfytlgerdrrdiylnvvmeyvpdtlhrccrnyyrrqv
apppilikvflfqlirsigclhlpsvnvchrdikphnvlvneadgtlklcdfgsakklsp
sepnvayicsryyrapelifgnqhyttsvdiwsvgcifaemmlgepifrgdnsagqlhei
vrvlgcpsrevlrklnpshtdvdlynskgipwssvfcdhslkdakeaydllsallqylpe
drmkpyealchpyfdelhdsatklpnnkdlpedlfrflpseievmseaqkaklvrk

    Sequence, based on observed residues (ATOM records): (download) 
    >7s6vA (A:)
mslnaadaadersrkemdrfqvermagqgtfgtvqlgkekstgmsvaikkviqdprfrnr
elqimqdlavlhhpnivqlqsyfytlgerdrrdiylnvvmeyvpdtlhrccrnyyrrqva
pppilikvflfqlirsigclhlpsvnvchrdikphnvlvneadgtlklcdfgsakklsps
epnvayicsryyrapelifgnqhyttsvdiwsvgcifaemmlgepifrgdnsagqlheiv
rvlgcpsrevlrklnynskgipwssvfcdhslkdakeaydllsallqylpedrmkpyeal
chpyfdelhdsatklpnnkdlpedlfrflpseievmseaqkaklv