PDB entry 7oji

View 7oji on RCSB PDB site
Description: abcg2 topotecan turnover-2 state
Deposited on 2021-05-16, released 2021-07-21
The last revision was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: EM
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Broad substrate specificity ATP-binding cassette transporter ABCG2
    Species: Homo sapiens [TaxId:9606]
    Gene: ABCG2, ABCP, BCRP, BCRP1, MXR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UNQ0 (11-664)
      • initiating methionine (0)
      • expression tag (1-10)
  • Chain 'B':
    Compound: Broad substrate specificity ATP-binding cassette transporter ABCG2
    Species: Homo sapiens [TaxId:9606]
    Gene: ABCG2, ABCP, BCRP, BCRP1, MXR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UNQ0 (11-664)
      • initiating methionine (0)
      • expression tag (1-10)
  • Heterogens: TTC, CLR, PLC, ATP

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7ojiA (A:)
mdykddddkgssssnvevfipvsqgntngfpatasndlkaftegavlsfhnicyrvklks
gflpcrkpvekeilsningimkpglnailgptgggksslldvlaarkdpsglsgdvling
aprpanfkcnsgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerinrviqelgl
dkvadskvgtqfirgvsggerkrtsigmelitdpsilfldepttgldsstanavllllkr
mskqgrtiifsihqprysifklfdsltllasgrlmfhgpaqealgyfesagyhceaynnp
adffldiingdstavalnreedfkateiiepskqdkplieklaeiyvnssfyketkaelh
qlsggekkkkitvfkeisyttsfchqlrwvskrsfknllgnpqasiaqiivtvvlglvig
aiyfglkndstgiqnragvlfflttnqcfssvsavelfvvekklfiheyisgyyrvssyf
lgkllsdllpmrmlpsiiftcivyfmlglkpkadaffvmmftlmmvaysassmalaiaag
qsvvsvatllmticfvfmmifsgllvnlttiaswlswlqyfsiprygftalqhneflgqn
fcpglnatgnnpcnyatctgeeylvkqgidlspwglwknhvalacmivifltiaylkllf
lkkys

    Sequence, based on observed residues (ATOM records):
    >7ojiA (A:)
gavlsfhnicyrvkpvekeilsningimkpglnailgptgggksslldvlaarkdpsgls
gdvlingaprpanfkcnsgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerinr
viqelgldkvadskvgtqfirgvsggerkrtsigmelitdpsilfldepttgldsstana
vllllkrmskqgrtiifsihqprysifklfdsltllasgrlmfhgpaqealgyfesagyh
ceaynnpadffldiingdkplieklaeiyvnssfyketkaelhqlsyttsfchqlrwvsk
rsfknllgnpqasiaqiivtvvlglvigaiyfglkndstgiqnragvlfflttnqcfssv
savelfvvekklfiheyisgyyrvssyflgkllsdllpmrmlpsiiftcivyfmlglkpk
adaffvmmftlmmvaysassmalaiaagqsvvsvatllmticfvfmmifsgllvnlttia
swlswlqyfsiprygftalqhneflgqnfcpglnatgnnpcnyatctgeeylvkqgidls
pwglwknhvalacmivifltiaylkllflkky

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7ojiB (B:)
mdykddddkgssssnvevfipvsqgntngfpatasndlkaftegavlsfhnicyrvklks
gflpcrkpvekeilsningimkpglnailgptgggksslldvlaarkdpsglsgdvling
aprpanfkcnsgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerinrviqelgl
dkvadskvgtqfirgvsggerkrtsigmelitdpsilfldepttgldsstanavllllkr
mskqgrtiifsihqprysifklfdsltllasgrlmfhgpaqealgyfesagyhceaynnp
adffldiingdstavalnreedfkateiiepskqdkplieklaeiyvnssfyketkaelh
qlsggekkkkitvfkeisyttsfchqlrwvskrsfknllgnpqasiaqiivtvvlglvig
aiyfglkndstgiqnragvlfflttnqcfssvsavelfvvekklfiheyisgyyrvssyf
lgkllsdllpmrmlpsiiftcivyfmlglkpkadaffvmmftlmmvaysassmalaiaag
qsvvsvatllmticfvfmmifsgllvnlttiaswlswlqyfsiprygftalqhneflgqn
fcpglnatgnnpcnyatctgeeylvkqgidlspwglwknhvalacmivifltiaylkllf
lkkys

    Sequence, based on observed residues (ATOM records):
    >7ojiB (B:)
gavlsfhnicyrvkpvekeilsningimkpglnailgptgggksslldvlaarkdpsgls
gdvlingaprpanfkcnsgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerinr
viqelgldkvadskvgtqfirgvsggerkrtsigmelitdpsilfldepttgldsstana
vllllkrmskqgrtiifsihqprysifklfdsltllasgrlmfhgpaqealgyfesagyh
ceaynnpadffldiingdkplieklaeiyvnssfyketkaelhqlsyttsfchqlrwvsk
rsfknllgnpqasiaqiivtvvlglvigaiyfglkndstgiqnragvlfflttnqcfssv
savelfvvekklfiheyisgyyrvssyflgkllsdllpmrmlpsiiftcivyfmlglkpk
adaffvmmftlmmvaysassmalaiaagqsvvsvatllmticfvfmmifsgllvnlttia
swlswlqyfsiprygftalqhneflgqnfcpglnatgnnpcnyatctgeeylvkqgidls
pwglwknhvalacmivifltiaylkllflkky