PDB entry 7o5o

View 7o5o on RCSB PDB site
Description: 14-3-3 sigma with rela/p65 binding site ps45 and covalently bound tcf521-165
Deposited on 2021-04-09, released 2021-06-09
The last revision was dated 2021-07-07, with a file datestamp of 2021-07-02.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 14-3-3 protein sigma
    Species: Homo sapiens [TaxId:9606]
    Gene: SFN, HME1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31947 (5-235)
      • expression tag (0-4)
  • Chain 'P':
    Compound: Transcription factor p65
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q04206 (0-12)
      • variant (10)
  • Heterogens: V3K, CL, GOL, CA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7o5oA (A:)
gamgsmerasliqkaklaeqaeryedmaafmkgavekgeelsceernllsvayknvvggq
raawrvlssieqksneegseekgpevreyrekvetelqgvcdtvlglldshlikeagdae
srvfylkmkgdyyrylaevatgddkkriidsarsayqeamdiskkempptnpirlglaln
fsvfhyeianspeeaislakttfdeamadlhtlsedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >7o5oA (A:)
mgsmerasliqkaklaeqaeryedmaafmkgavekgeelsceernllsvayknvvggqra
awrvlssieqksnegpevreyrekvetelqgvcdtvlglldshlikeagdaesrvfylkm
kgdyyrylaevatgddkkriidsarsayqeamdiskkempptnpirlglalnfsvfhyei
anspeeaislakttfdeamadlhtlsedsykdstlimqllrdnltlwt

  • Chain 'P':
    Sequence, based on SEQRES records:
    >7o5oP (P:)
egrsagsipgrrs

    Sequence, based on observed residues (ATOM records):
    >7o5oP (P:)
agsipgrrs