PDB entry 7npj

View 7npj on RCSB PDB site
Description: crystal structure of mycobacterium tuberculosis argc in complex with 6-phenoxy-3-pyridinamine
Deposited on 2021-02-27, released 2021-06-30
The last revision was dated 2021-06-30, with a file datestamp of 2021-06-25.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N-acetyl-gamma-glutamyl-phosphate reductase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argC, Rv1652, MTCY06H11.17
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: N-acetyl-gamma-glutamyl-phosphate reductase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argC, Rv1652, MTCY06H11.17
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: N-acetyl-gamma-glutamyl-phosphate reductase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argC, Rv1652, MTCY06H11.17
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: N-acetyl-gamma-glutamyl-phosphate reductase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argC, Rv1652, MTCY06H11.17
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: N-acetyl-gamma-glutamyl-phosphate reductase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argC, Rv1652, MTCY06H11.17
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: N-acetyl-gamma-glutamyl-phosphate reductase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argC, Rv1652, MTCY06H11.17
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: N-acetyl-gamma-glutamyl-phosphate reductase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argC, Rv1652, MTCY06H11.17
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: N-acetyl-gamma-glutamyl-phosphate reductase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argC, Rv1652, MTCY06H11.17
    Database cross-references and differences (RAF-indexed):
  • Heterogens: UKK

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7npjA (A:)
gsmqnrqvanatkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgeh
hphltplahrvvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltda
avwerfygsshagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliep
avtvvavsgtsgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvs
ftpvlipasrgilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsna
ahiavavdedaqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

    Sequence, based on observed residues (ATOM records):
    >7npjA (A:)
atkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgehhphltplahr
vvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltdaavwerfygss
hagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliepavtvvavsgt
sgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvsftpvlipasr
gilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsnaahiavavded
aqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7npjB (B:)
gsmqnrqvanatkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgeh
hphltplahrvvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltda
avwerfygsshagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliep
avtvvavsgtsgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvs
ftpvlipasrgilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsna
ahiavavdedaqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

    Sequence, based on observed residues (ATOM records):
    >7npjB (B:)
atkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgehhphltplahr
vvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltdaavwerfygss
hagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliepavtvvavsgt
sgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvsftpvlipasr
gilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsnaahiavavded
aqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7npjC (C:)
gsmqnrqvanatkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgeh
hphltplahrvvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltda
avwerfygsshagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliep
avtvvavsgtsgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvs
ftpvlipasrgilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsna
ahiavavdedaqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

    Sequence, based on observed residues (ATOM records):
    >7npjC (C:)
atkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgehhphltplahr
vvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltdaavwerfygss
hagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliepavtvvavsgt
sgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvsftpvlipasr
gilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsnaahiavavded
aqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7npjD (D:)
gsmqnrqvanatkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgeh
hphltplahrvvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltda
avwerfygsshagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliep
avtvvavsgtsgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvs
ftpvlipasrgilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsna
ahiavavdedaqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

    Sequence, based on observed residues (ATOM records):
    >7npjD (D:)
atkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgehhphltplahr
vvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltdaavwerfygss
hagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliepavtvvavsgt
sgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvsftpvlipasr
gilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsnaahiavavded
aqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7npjE (E:)
gsmqnrqvanatkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgeh
hphltplahrvvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltda
avwerfygsshagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliep
avtvvavsgtsgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvs
ftpvlipasrgilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsna
ahiavavdedaqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

    Sequence, based on observed residues (ATOM records):
    >7npjE (E:)
atkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgehhphltplahr
vvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltdaavwerfygss
hagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliepavtvvavsgt
sgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvsftpvlipasr
gilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsnaahiavavded
aqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

  • Chain 'F':
    Sequence, based on SEQRES records:
    >7npjF (F:)
gsmqnrqvanatkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgeh
hphltplahrvvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltda
avwerfygsshagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliep
avtvvavsgtsgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvs
ftpvlipasrgilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsna
ahiavavdedaqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

    Sequence, based on observed residues (ATOM records):
    >7npjF (F:)
atkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgehhphltplahr
vvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltdaavwerfygss
hagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliepavtvvavsgt
sgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvsftpvlipasr
gilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsnaahiavavded
aqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7npjG (G:)
gsmqnrqvanatkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgeh
hphltplahrvvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltda
avwerfygsshagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliep
avtvvavsgtsgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvs
ftpvlipasrgilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsna
ahiavavdedaqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

    Sequence, based on observed residues (ATOM records):
    >7npjG (G:)
atkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgehhphltplahr
vvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltdaavwerfygss
hagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliepavtvvavsgt
sgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvsftpvlipasr
gilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsnaahiavavded
aqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

  • Chain 'H':
    Sequence, based on SEQRES records:
    >7npjH (H:)
gsmqnrqvanatkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgeh
hphltplahrvvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltda
avwerfygsshagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliep
avtvvavsgtsgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvs
ftpvlipasrgilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsna
ahiavavdedaqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap

    Sequence, based on observed residues (ATOM records):
    >7npjH (H:)
atkvavagasgyaggeilrlllghpayadgrlrigaltaatsagstlgehhphltplahr
vvepteaavlgghdavflalphghsavlaqqlspetliidcgadfrltdaavwerfygss
hagswpyglpelpgardqlrgtrriavpgcyptaallalfpalaadliepavtvvavsgt
sgagraattdllgaevigsarayniagvhrhtpeiaqglravtdrdvsvsftpvlipasr
gilatctartrsplsqlraayekayhaepfiylmpegqlprtgavigsnaahiavavded
aqtfvaiaaidnlvkgtagaavqsmnlalgwpetdglsvvgvap