PDB entry 7np6

View 7np6 on RCSB PDB site
Description: ROR(gamma)t ligand binding domain in complex with allosteric ligand FM257
Class: nuclear protein
Keywords: Nuclear receptor, Retinoic acid receptor-related orphan receptor gamma t, inverse agonist, NUCLEAR PROTEIN
Deposited on 2021-02-26, released 2021-06-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-06-02, with a file datestamp of 2021-05-28.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor ROR-gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: RORC, NR1F3, RORG, RZRG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51449 (Start-246)
      • engineered mutation (194)
    Domains in SCOPe 2.07: d7np6a_
  • Heterogens: UK8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7np6A (A:)
gshmaslteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwerc
ahhlteaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffeg
kyggmelfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkve
qlqynlelafhhhlhkthrqsilaklppkgklrslcsqhverlqifqhlhpivvqaafpp
lykelfs

    Sequence, based on observed residues (ATOM records): (download) 
    >7np6A (A:)
slteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwercahhlt
eaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegkyggm
elfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveqlqyn
lelafhhhlhkthrqsilaklppkgklrslcsqhverlqifqhlhpivvqaafpplykel
fs