PDB entry 7n8h

View 7n8h on RCSB PDB site
Description: SARS-CoV-2 S (B.1.429 / epsilon variant) + S2M11 + S2L20 Global Refinement
Class: viral protein/immune system
Keywords: coronavirus, antibody, california, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, SSGCID, VIRAL PROTEIN, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2021-06-14, released 2021-07-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: EM
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (0-1207)
      • conflict (12)
      • conflict (151)
      • conflict (451)
      • conflict (681-682)
      • conflict (684)
      • conflict (816)
      • conflict (891)
      • conflict (898)
      • conflict (941)
      • conflict (985-986)
      • expression tag (1208-1276)
  • Chain 'B':
    Compound: S2L20 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-105)
    Domains in SCOPe 2.08: d7n8hb_
  • Chain 'C':
    Compound: S2L20 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-120)
    Domains in SCOPe 2.08: d7n8hc_
  • Chain 'D':
    Compound: S2M11 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-103)
    Domains in SCOPe 2.08: d7n8hd_
  • Chain 'E':
    Compound: S2M11 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-121)
    Domains in SCOPe 2.08: d7n8he_
  • Chain 'F':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (0-1207)
      • conflict (12)
      • conflict (151)
      • conflict (451)
      • conflict (681-682)
      • conflict (684)
      • conflict (816)
      • conflict (891)
      • conflict (898)
      • conflict (941)
      • conflict (985-986)
      • expression tag (1208-1276)
  • Chain 'G':
    Compound: S2M11 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-103)
    Domains in SCOPe 2.08: d7n8hg_
  • Chain 'H':
    Compound: S2M11 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-121)
    Domains in SCOPe 2.08: d7n8hh_
  • Chain 'I':
    Compound: S2L20 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-105)
    Domains in SCOPe 2.08: d7n8hi_
  • Chain 'J':
    Compound: S2L20 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-120)
    Domains in SCOPe 2.08: d7n8hj_
  • Chain 'K':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (0-1207)
      • conflict (12)
      • conflict (151)
      • conflict (451)
      • conflict (681-682)
      • conflict (684)
      • conflict (816)
      • conflict (891)
      • conflict (898)
      • conflict (941)
      • conflict (985-986)
      • expression tag (1208-1276)
  • Chain 'L':
    Compound: S2M11 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-103)
    Domains in SCOPe 2.08: d7n8hl_
  • Chain 'M':
    Compound: S2M11 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-121)
    Domains in SCOPe 2.08: d7n8hm_
  • Chain 'N':
    Compound: S2L20 Fab Light Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-105)
    Domains in SCOPe 2.08: d7n8hn_
  • Chain 'O':
    Compound: S2L20 Fab Heavy Chain variable region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7N8H (0-120)
    Domains in SCOPe 2.08: d7n8ho_
  • Heterogens: FUC, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hB (B:)
viwmtqspsslsasvgdrvtitcqasqdirfylnwyqqkpgkapkllisdasnmetgvps
rfsgsgsgtdftftisslqpediatyycqqydnlpftfgpgtkvdf

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hC (C:)
evqlvesgggvvqpggslrlscaasgftfnsygmhwvrqapgkglewvafirydggnkyy
adsvkgrftisrdnskntlylqmkslraedtavyycanlkdsrysgsyydywgqgtlvtv
s

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hD (D:)
ivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgipd
rfsgsgsgtdftltisrlepedfavyycqqygssawtfgqgtkv

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hE (E:)
vqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpissgtsya
qtfqgrvtmtsdtsittaymelsrlrsddtavyycaraapfydfwsgysyfdywgqgtlv
tv

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hG (G:)
ivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgipd
rfsgsgsgtdftltisrlepedfavyycqqygssawtfgqgtkv

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hH (H:)
vqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpissgtsya
qtfqgrvtmtsdtsittaymelsrlrsddtavyycaraapfydfwsgysyfdywgqgtlv
tv

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hI (I:)
viwmtqspsslsasvgdrvtitcqasqdirfylnwyqqkpgkapkllisdasnmetgvps
rfsgsgsgtdftftisslqpediatyycqqydnlpftfgpgtkvdf

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hJ (J:)
evqlvesgggvvqpggslrlscaasgftfnsygmhwvrqapgkglewvafirydggnkyy
adsvkgrftisrdnskntlylqmkslraedtavyycanlkdsrysgsyydywgqgtlvtv
s

  • Chain 'K':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hL (L:)
ivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgipd
rfsgsgsgtdftltisrlepedfavyycqqygssawtfgqgtkv

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hM (M:)
vqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpissgtsya
qtfqgrvtmtsdtsittaymelsrlrsddtavyycaraapfydfwsgysyfdywgqgtlv
tv

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hN (N:)
viwmtqspsslsasvgdrvtitcqasqdirfylnwyqqkpgkapkllisdasnmetgvps
rfsgsgsgtdftftisslqpediatyycqqydnlpftfgpgtkvdf

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7n8hO (O:)
evqlvesgggvvqpggslrlscaasgftfnsygmhwvrqapgkglewvafirydggnkyy
adsvkgrftisrdnskntlylqmkslraedtavyycanlkdsrysgsyydywgqgtlvtv
s