PDB entry 7n44
View 7n44 on RCSB PDB site
Description: Crystal structure of the SARS-CoV-2 (2019-NCoV) main protease in complex with 5-(3-{3-chloro-5-[(5-methyl-1,3-thiazol-4-yl)methoxy]phenyl}-2-oxo-2H-[1,3'-bipyridin]-5-yl)pyrimidine-2,4(1H,3H)-dione (compound 13)
Class: hydrolase
Keywords: novel coronavirus, antiviral, drug design, viral protein, HYDROLASE
Deposited on
2021-06-03, released
2021-07-21
The last revision prior to the SCOPe 2.08 freeze date was dated
2021-07-21, with a file datestamp of
2021-07-16.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: N/A
AEROSPACI score: 0.39
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 3C-like proteinase
Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
Gene: rep, 1a-1b
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d7n44a_ - Heterogens: 06I, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>7n44A (A:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllir
ksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegn
fygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqc
sgvtfq
Sequence, based on observed residues (ATOM records): (download)
>7n44A (A:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvicedmlnpnyedllirks
nhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyngsp
sgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegnfy
gpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnftttlndfnlvamkynyeplt
qdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqcs