PDB entry 7n3b

View 7n3b on RCSB PDB site
Description: Crystal structure of aged 9-site deamidated variant of human gamma(S)-crystallin
Class: structural protein
Keywords: structural protein, crystallin, human crystallin, gamma(S) crystallin, eye lens protein
Deposited on 2021-05-31, released 2022-03-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-10-05, with a file datestamp of 2022-09-30.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Gamma-crystallin S
    Species: Homo sapiens [TaxId:9606]
    Gene: CRYGS, CRYG8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22914 (1-177)
      • expression tag (0)
      • engineered mutation (14)
      • engineered mutation (16)
      • engineered mutation (53)
      • engineered mutation (63)
      • engineered mutation (70)
      • engineered mutation (92)
      • engineered mutation (106)
      • engineered mutation (120)
      • engineered mutation (143)
    Domains in SCOPe 2.08: d7n3ba1, d7n3ba2
  • Chain 'B':
    Compound: Gamma-crystallin S
    Species: Homo sapiens [TaxId:9606]
    Gene: CRYGS, CRYG8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22914 (1-177)
      • expression tag (0)
      • engineered mutation (14)
      • engineered mutation (16)
      • engineered mutation (53)
      • engineered mutation (63)
      • engineered mutation (70)
      • engineered mutation (92)
      • engineered mutation (106)
      • engineered mutation (120)
      • engineered mutation (143)
    Domains in SCOPe 2.08: d7n3bb1, d7n3bb2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7n3bA (A:)
gsktgtkitfyedkdfegrrydcdcdcadfhtylsrcnsikveggtwavyerpdfagymy
ilpegeypeyerwmglndrlsscravhlpsggeykiqifekgdfsgemyettedcpsime
efhmreihsckvlegvwifyelpdyrgrqylldkkeyrkpidwgaaspavqsfrrive

    Sequence, based on observed residues (ATOM records): (download) 
    >7n3bA (A:)
gtkitfyedkdfegrrydcdcdcadfhtylsrcnsikveggtwavyerpdfagymyilpe
geypeyerwmglndrlsscravhlpsggeykiqifekgdfsgemyettedcpsimeefhm
reihsckvlegvwifyelpdyrgrqylldkkeyrkpidwgaaspavqsfrrive

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7n3bB (B:)
gsktgtkitfyedkdfegrrydcdcdcadfhtylsrcnsikveggtwavyerpdfagymy
ilpegeypeyerwmglndrlsscravhlpsggeykiqifekgdfsgemyettedcpsime
efhmreihsckvlegvwifyelpdyrgrqylldkkeyrkpidwgaaspavqsfrrive

    Sequence, based on observed residues (ATOM records): (download) 
    >7n3bB (B:)
gtkitfyedkdfegrrydcdcdcadfhtylsrcnsikveggtwavyerpdfagymyilpe
geypeyerwmglndrlsscravhlpsggeykiqifekgdfsgemyettedcpsimeefhm
reihsckvlegvwifyelpdyrgrqylldkkeyrkpidwgaaspavqsfrrive