PDB entry 7myr

View 7myr on RCSB PDB site
Description: bace-1 in complex with compound #18
Deposited on 2021-05-21, released 2021-07-14
The last revision was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-secretase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BACE1, BACE, KIAA1149
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56817 (1-441)
      • expression tag (0)
  • Chain 'B':
    Compound: Beta-secretase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BACE1, BACE, KIAA1149
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56817 (1-441)
      • expression tag (0)
  • Heterogens: ZRD, GOL, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7myrA (A:)
magvlpahgtqhgirlplrsglggaplglrlpretdeepeepgrrgsfvemvdnlrgksg
qgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhryyqrqlsstyrdlrkgvyvpy
tqgkwegelgtdlvsiphgpnvtvraniaaitesdkffingsnwegilglayaeiarpdd
slepffdslvkqthvpnlfslqlcgagfplnqsevlasvggsmiiggidhslytgslwyt
pirrewyyeviivrveingqdlkmdckeynydksivdsgttnlrlpkkvfeaavksikaa
sstekfpdgfwlgeqlvcwqagttpwnifpvislylmgevtnqsfritilpqqylrpved
vatsqddcykfaisqsstgtvmgavimegfyvvfdrarkrigfavsachvhdefrtaave
gpfvtldmedcgynipqtdest

    Sequence, based on observed residues (ATOM records):
    >7myrA (A:)
rrgsfvemvdnlrgksgqgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhryyqr
qlsstyrdlrkgvyvpytqgkwegelgtdlvsiphgpnvtvraniaaitesdkffingsn
wegilglayaeiarpddslepffdslvkqthvpnlfslqlcgagfplnqsevlasvggsm
iiggidhslytgslwytpirrewyyeviivrveingqdlkmdckeynydksivdsgttnl
rlpkkvfeaavksikaasstekfpdgfwlgeqlvcwqagttpwnifpvislylmgevtnq
sfritilpqqylrpvedvatsqddcykfaisqsstgtvmgavimegfyvvfdrarkrigf
avsachvhdefrtaavegpfvtldmedcgyn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7myrB (B:)
magvlpahgtqhgirlplrsglggaplglrlpretdeepeepgrrgsfvemvdnlrgksg
qgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhryyqrqlsstyrdlrkgvyvpy
tqgkwegelgtdlvsiphgpnvtvraniaaitesdkffingsnwegilglayaeiarpdd
slepffdslvkqthvpnlfslqlcgagfplnqsevlasvggsmiiggidhslytgslwyt
pirrewyyeviivrveingqdlkmdckeynydksivdsgttnlrlpkkvfeaavksikaa
sstekfpdgfwlgeqlvcwqagttpwnifpvislylmgevtnqsfritilpqqylrpved
vatsqddcykfaisqsstgtvmgavimegfyvvfdrarkrigfavsachvhdefrtaave
gpfvtldmedcgynipqtdest

    Sequence, based on observed residues (ATOM records):
    >7myrB (B:)
gsfvemvdnlrgksgqgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhryyqrql
sstyrdlrkgvyvpytqgkwegelgtdlvsiphgpnvtvraniaaitesdkffingsnwe
gilglayaeiarpddslepffdslvkqthvpnlfslqlcgagfplnqsevlasvggsmii
ggidhslytgslwytpirrewyyeviivrveingqdlkmdckeynydksivdsgttnlrl
pkkvfeaavksikaasstekfpdgfwlgeqlvcwqagttpwnifpvislylmgevtnqsf
ritilpqqylrpvedvatsqddcykfaisqsstgtvmgavimegfyvvfdrarkrigfav
sachvhdefrtaavegpfvtldmedcgyn