PDB entry 7mtq

View 7mtq on RCSB PDB site
Description: cryoem structure of full-length mglu2 in inactive-state bound to antagonist ly341495
Deposited on 2021-05-13, released 2021-07-07
The last revision was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: EM
Resolution: 3.65 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Metabotropic glutamate receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: GRM2, GPRC1B, MGLUR2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Metabotropic glutamate receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: GRM2, GPRC1B, MGLUR2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: Z99, NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7mtqA (A:)
aegpakkvltlegdlvlgglfpvhqkggpaedcgpvnehrgiqrleamlfaldrinrdph
llpgvrlgahildscskdthaleqaldfvraslsrgadgsrhicpdgsyathgdaptait
gviggsysdvsiqvanllrlfqipqisyastsaklsdksrydyfartvppdffqakamae
ilrffnwtyvstvasegdygetgieafeleararnicvatsekvgramsraafegvvral
lqkpsarvavlftrsedarellaasqrlnasftwvasdgwgalesvvagsegaaegaiti
elasypisdfasyfqsldpwnnsrnpwfrefweqrfrcsfrqrdcaahslravpfeqesk
imfvvnavyamahalhnmhralcpnttrlcdamrpvngrrlykdfvlnvkfdapfrpadt
hnevrfdrfgdgigryniftylragsgryryqkvgywaegltldtslipwaspsagplpa
srcsepclqnevksvqpgevccwlcipcqpyeyrldeftcadcglgywpnasltgcfelp
qeyirwgdawavgpvtiaclgalatlfvlgvfvrhnatpvvkasgrelcyillggvflcy
cmtfifiakpstavctlrrlglgtafsvcysalltktnriarifggaregaqrprfispa
sqvaiclalisgqllivvawlvveapgtgketaperrevvtlrcnhrdasmlgslaynvl
lialctlyafktrkcpenfneakfigftmyttciiwlaflpifyvtssdyrvqtttmcvs
vslsgsvvlgclfapklhiilfqpqknvvshraptsrfgsaaarassslgqgsgsqfvpt
vcngrevvdsttssl

    Sequence, based on observed residues (ATOM records):
    >7mtqA (A:)
kvltlegdlvlgglfpvhqkpaedcgpvnehrgiqrleamlfaldrinrdphllpgvrlg
ahildscskdthaleqaldfvraslptaitgviggsysdvsiqvanllrlfqipqisyas
tsaklsdksrydyfartvppdffqakamaeilrffnwtyvstvasegdygetgieafele
ararnicvatsekvgramsraafegvvrallqkpsarvavlftrsedarellaasqrlna
sftwvasdgwgalesvvagsegaaegaitielasypisdfasyfqsldpwnnsrnpwfre
fweqrfrcsfrqrdcaahslravpfeqeskimfvvnavyamahalhnmhralcpnttrlc
damrpvngrrlykdfvlnvkfdapfrpadthnevrfdrfgdgigryniftylragsgryr
yqkvgywaegltldtslipwasagplpasrcsepclqnevksvqevccwlcipcqyelde
ftcadcglgwpnltgcfelpqeyirwdawavgpvtiaclgalatlfvlgvfvrhnatpvv
kasgrelcyillggvflcycmtfifiakpstavctlrrlglgtafsvcysalltktnria
rspasqvaiclalisgqllivvawlvveapgtetaperrevvtlrcnhrdasmlgslayn
vllilctlyafktrkcpenfneakfigftmyttciiwlaflpifyvtssdyrvqtttmcv
svslsgsvvlgclfapklhiil

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7mtqB (B:)
aegpakkvltlegdlvlgglfpvhqkggpaedcgpvnehrgiqrleamlfaldrinrdph
llpgvrlgahildscskdthaleqaldfvraslsrgadgsrhicpdgsyathgdaptait
gviggsysdvsiqvanllrlfqipqisyastsaklsdksrydyfartvppdffqakamae
ilrffnwtyvstvasegdygetgieafeleararnicvatsekvgramsraafegvvral
lqkpsarvavlftrsedarellaasqrlnasftwvasdgwgalesvvagsegaaegaiti
elasypisdfasyfqsldpwnnsrnpwfrefweqrfrcsfrqrdcaahslravpfeqesk
imfvvnavyamahalhnmhralcpnttrlcdamrpvngrrlykdfvlnvkfdapfrpadt
hnevrfdrfgdgigryniftylragsgryryqkvgywaegltldtslipwaspsagplpa
srcsepclqnevksvqpgevccwlcipcqpyeyrldeftcadcglgywpnasltgcfelp
qeyirwgdawavgpvtiaclgalatlfvlgvfvrhnatpvvkasgrelcyillggvflcy
cmtfifiakpstavctlrrlglgtafsvcysalltktnriarifggaregaqrprfispa
sqvaiclalisgqllivvawlvveapgtgketaperrevvtlrcnhrdasmlgslaynvl
lialctlyafktrkcpenfneakfigftmyttciiwlaflpifyvtssdyrvqtttmcvs
vslsgsvvlgclfapklhiilfqpqknvvshraptsrfgsaaarassslgqgsgsqfvpt
vcngrevvdsttssl

    Sequence, based on observed residues (ATOM records):
    >7mtqB (B:)
kvltlegdlvlgglfpvhqkpaedcgpvnehrgiqrleamlfaldrinrdphllpgvrlg
ahildscskdthaleqaldfvraslptaitgviggsysdvsiqvanllrlfqipqisyas
tsaklsdksrydyfartvppdffqakamaeilrffnwtyvstvasegdygetgieafele
ararnicvatsekvgramsraafegvvrallqkpsarvavlftrsedarellaasqrlna
sftwvasdgwgalesvvagsegaaegaitielasypisdfasyfqsldpwnnsrnpwfre
fweqrfrcsfrqrdcaahslravpfeqeskimfvvnavyamahalhnmhralcpnttrlc
damrpvngrrlykdfvlnvkfdapfrpadthnevrfdrfgdgigryniftylraggryry
qkvgywaegltldtslipwaspsagplpasrcseplqnevksvqpevccwlcipqpyerl
deftcadglgpnasltgcfelpqeyirwgdwavgpvtiaclgalatlfvlgvfvrhntvv
kasgrelcyillggvflcycmtfifiakpstavctlrrlglgtafsvcysalltktnria
riffispasqvaiclalisgqllivvawlvveapgttapevvtlrcnhrdasmlgslayn
vllialctlyafktrkcpenfneakfigftmyttciiwlaflpifyvtssdyrvqtttmc
vsvslsgsvvlgclfapklhiilf