PDB entry 7mta

View 7mta on RCSB PDB site
Description: rhodopsin kinase (grk1)-s5e/s488e/t489e in complex with rhodopsin and fab1
Deposited on 2021-05-13, released 2021-07-07
The last revision was dated 2021-08-25, with a file datestamp of 2021-08-20.
Experiment type: EM
Resolution: 4.1 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'G':
    Compound: Rhodopsin kinase GRK1
    Species: Bos taurus [TaxId:9913]
    Gene: GRK1, RHOK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28327 (0-534)
      • engineered mutation (4)
      • engineered mutation (487-488)
      • expression tag (535-542)
  • Chain 'H':
    Compound: Fab1 Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7MTA (0-233)
  • Chain 'L':
    Compound: Fab1 Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7MTA (0-216)
  • Chain 'R':
    Compound: rhodopsin
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SGV, RET

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7mtaG (G:)
mdfgeletvvansafiaargsfdassgpasrdrkylarlklpplskcealresldlgfeg
mcleqpigkrlfqqflrtheqhgpalqlwkdiedydtaddalrpqkaqalraaylepqaq
lfcsfldaetvararagagdglfqpllravlahlgqapfqefldslyflrflqwkwleaq
pmgedwfldfrvlgrggfgevfacqmkatgklyackklnkkrlkkrkgyqgamvekkila
kvhsrfivslayafetktdlclvmtimnggdiryhiynvdednpgfqepraifytaqivs
glehlhqrniiyrdlkpenvlldddgnvrisdlglavelkagqtktkgyagtpgfmapel
llgeeydfsvdyfalgvtlyemiaargpfrargekvenkelkqrvleqavtypdkfspas
kdfceallqkdpekrlgfrdgscdglrthplfrdiswrqleagmltppfvpdsrtvyakn
iqdvgafeevkgvafekadteffqefasgtcpipwqeemietgvfgdlnvwrpdgvdhhh
hhh

    Sequence, based on observed residues (ATOM records):
    >7mtaG (G:)
letvvansafiaargsfdamgedwfldfrvlgrggfgevfacqmkatgklyackklnkkr
lkkrkgyqgamvekkilakvhsrfivslayafetktdlclvmtimnggdiryhiynvded
npgfqepraifytaqivsglehlhqrniiyrdlkpenvlldddgnvrisdlglavelkag
qtktkgyagtpgfmapelllgeeydfsvdyfalgvtlyemiaargpfrargekvenkelk
qrvleqavtypdkfspaskdfceallqkdpekrlgfrdgscdglrthplfrdiswrqlea
gmltppfvpdsrtvyakniqdvgafeevkgvafekadteffqefas

  • Chain 'H':
    Sequence, based on SEQRES records:
    >7mtaH (H:)
eisevqlvesggglvqpggslrlscaasgfnlysssihwvrqapgkglewvasiysyygs
tsyadsvkgrftisadtskntaylqmnslraedtavyycaryegwwwantyaldywgqgt
lvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfp
avlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdktht

    Sequence, based on observed residues (ATOM records):
    >7mtaH (H:)
evqlvesggglvqpggslrlscaasgfnlysssihwvrqapgkglewvasiysyygstsy
adsvkgrftisadtskntaylqmnslraedtavyycaryegwwwantyaldywgqgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'L':
    Sequence, based on SEQRES records:
    >7mtaL (L:)
sdiqmtqspsslsasvgdrvtitcrasqsvssavawyqqkpgkapklliysasslysgvp
srfsgsrsgtdftltisslqpedfatyycqqyyewlslftfgqgtkveikrtvaapsvfi
fppsdsqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslss
tltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >7mtaL (L:)
diqmtqspsslsasvgdrvtitcrasqsvssavawyqqkpgkapklliysasslysgvps
rfsgsrsgtdftltisslqpedfatyycqqyyewlslftfgqgtkveikrtvaapsvfif
ppsdsqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsst
ltlskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'R':
    Sequence, based on SEQRES records:
    >7mtaR (R:)
mngtegpnfyvpfsnktgvvrspfeapqyylaepwqfsmlaaymfllimlgfpinfltly
vtvqhkklrtplnyillnlavadlfmvfggftttlytslhgyfvfgptgcnlegffatlg
geialwslvvlaieryvvvckpmsnfrfgenhaimgvaftwvmalacaapplvgwsryip
egmqcscgidyytpheetnnesfviymfvvhfiipliviffcygqlvftvkeaaaqqqes
attqkaekevtrmviimviaflicwlpyagvafyifthqgsdfgpifmtipaffaktsav
ynpviyimmnkqfrncmvttlccgknplgddeasttvsktetsqvapa

    Sequence, based on observed residues (ATOM records):
    >7mtaR (R:)
mngtegpnfyvpfsnktgvvrspfeapqyylaepwqfsmlaaymfllimlgfpinfltly
vtvqhkklrtplnyillnlavadlfmvfggftttlytslhgyfvfgptgcnlegffatlg
geialwslvvlaieryvvvckpmsnfrfgenhaimgvaftwvmalacaapplvgwsryip
egmqcscgidyytpheetnnesfviymfvvhfiipliviffcygqlvftvkeaaaqqqes
attqkaekevtrmviimviaflicwlpyagvafyifthqgsdfgpifmtipaffaktsav
ynpviyimmnkqfrncmvttlccg