PDB entry 7mjh

View 7mjh on RCSB PDB site
Description: cryo-em structure of the sars-cov-2 n501y mutant spike protein ectodomain bound to vh ab8
Deposited on 2021-04-20, released 2021-05-12
The last revision was dated 2021-05-12, with a file datestamp of 2021-05-07.
Experiment type: EM
Resolution: 2.66 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (500)
      • conflict (816)
      • conflict (891)
      • conflict (898)
      • conflict (941)
      • conflict (985-986)
  • Chain 'B':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (500)
      • conflict (816)
      • conflict (891)
      • conflict (898)
      • conflict (941)
      • conflict (985-986)
  • Chain 'C':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (500)
      • conflict (816)
      • conflict (891)
      • conflict (898)
      • conflict (941)
      • conflict (985-986)
  • Chain 'D':
    Compound: VH ab8
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 7MJH (0-End)
  • Chain 'E':
    Compound: VH ab8
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 7MJH (0-End)
  • Chain 'F':
    Compound: VH ab8
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 7MJH (0-End)
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7mjhA (A:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptygvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnspgsassvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrspiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagpalqipfpm
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstpsalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqgsgyipeaprdgqayvrkdgewvllstflgrslevlfqgpghhhhhhhhsaw
shpqfekgggsggggsggsawshpqfek

    Sequence, based on observed residues (ATOM records):
    >7mjhA (A:)
qcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihkrfd
npvlpfndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpf
lgvyymesefrvyssannctfeyvsqpflnfknlrefvfknidgyfkiyskhtpinlvrd
lpqgfsaleplvdlpiginitrfqtllalhrsgwtagaaayyvgylqprtfllkynengt
itdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfna
trfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirg
devrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpf
erdisteiyqagstpcngvegfncyfplqsygfqptygvgyqpyrvvvlsfellhapatv
cgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtlei
lditpcsfggvsvitpgtntsnqvavlyqdvnctevnvfqtragcligaehvnnsyecdi
pigagicasyqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdct
myicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfgg
fnfsqilpdpskpskrspiedllfnkvtngltvlpplltdemiaqytsallagtitsgwt
fgagpalqipfpmqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstpsalgk
lqdvvnqnaqalntlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqty
vtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvty
vpaqeknfttapaichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncd
vvigivnntvydplqpelds

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7mjhB (B:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptygvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnspgsassvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrspiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagpalqipfpm
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstpsalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqgsgyipeaprdgqayvrkdgewvllstflgrslevlfqgpghhhhhhhhsaw
shpqfekgggsggggsggsawshpqfek

    Sequence, based on observed residues (ATOM records):
    >7mjhB (B:)
qcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihkrfd
npvlpfndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpf
lgvyymesefrvyssannctfeyvsqpflnfknlrefvfknidgyfkiyskhtpinlvrd
lpqgfsaleplvdlpiginitrfqtllalhrsgwtagaaayyvgylqprtfllkynengt
itdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfna
trfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirg
devrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpf
erdisteiyqagstpcngvegfncyfplqsygfqptygvgyqpyrvvvlsfellhapatv
cgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtlei
lditpcsfggvsvitpgtntsnqvavlyqdvnctevnvfqtragcligaehvnnsyecdi
pigagicasyqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdct
myicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfgg
fnfsqilpdpskpskrspiedllfnkvtngltvlpplltdemiaqytsallagtitsgwt
fgagpalqipfpmqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstpsalgk
lqdvvnqnaqalntlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqty
vtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvty
vpaqeknfttapaichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncd
vvigivnntvydplqpelds

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7mjhC (C:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptygvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnspgsassvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrspiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagpalqipfpm
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstpsalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqgsgyipeaprdgqayvrkdgewvllstflgrslevlfqgpghhhhhhhhsaw
shpqfekgggsggggsggsawshpqfek

    Sequence, based on observed residues (ATOM records):
    >7mjhC (C:)
qcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihkrfd
npvlpfndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpf
lgvyymesefrvyssannctfeyvsqpflnfknlrefvfknidgyfkiyskhtpinlvrd
lpqgfsaleplvdlpiginitrfqtllalhrsgwtagaaayyvgylqprtfllkynengt
itdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfna
trfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirg
devrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpf
erdisteiyqagstpcngvegfncyfplqsygfqptygvgyqpyrvvvlsfellhapatv
cgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtlei
lditpcsfggvsvitpgtntsnqvavlyqdvnctevnvfqtragcligaehvnnsyecdi
pigagicasyqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdct
myicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfgg
fnfsqilpdpskpskrspiedllfnkvtngltvlpplltdemiaqytsallagtitsgwt
fgagpalqipfpmqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstpsalgk
lqdvvnqnaqalntlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqty
vtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvty
vpaqeknfttapaichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncd
vvigivnntvydplqpelds

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7mjhD (D:)
evqlvesggglvqpggslrlscaasgftfddyamswvrqapgkglewigrmynngrtsyn
pslkslvtisrdnskntlylqmnslraedtatyycardnlgyrpsenlygmdvwgqgttv
tvsssgqaghhhhhhgdykddddkg

    Sequence, based on observed residues (ATOM records):
    >7mjhD (D:)
evqlvesggglvqpggslrlscaasgftfddyamswvrqapgkglewigrmynngrtsyn
pslkslvtisrdnskntlylqmnslraedtatyycardnlgyrpsenlygmdvwgqgttv
tvsss

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7mjhE (E:)
evqlvesggglvqpggslrlscaasgftfddyamswvrqapgkglewigrmynngrtsyn
pslkslvtisrdnskntlylqmnslraedtatyycardnlgyrpsenlygmdvwgqgttv
tvsssgqaghhhhhhgdykddddkg

    Sequence, based on observed residues (ATOM records):
    >7mjhE (E:)
evqlvesggglvqpggslrlscaasgftfddyamswvrqapgkglewigrmynngrtsyn
pslkslvtisrdnskntlylqmnslraedtatyycardnlgyrpsenlygmdvwgqgttv
tvsss

  • Chain 'F':
    Sequence, based on SEQRES records:
    >7mjhF (F:)
evqlvesggglvqpggslrlscaasgftfddyamswvrqapgkglewigrmynngrtsyn
pslkslvtisrdnskntlylqmnslraedtatyycardnlgyrpsenlygmdvwgqgttv
tvsssgqaghhhhhhgdykddddkg

    Sequence, based on observed residues (ATOM records):
    >7mjhF (F:)
evqlvesggglvqpggslrlscaasgftfddyamswvrqapgkglewigrmynngrtsyn
pslkslvtisrdnskntlylqmnslraedtatyycardnlgyrpsenlygmdvwgqgttv
tvsss