PDB entry 7mfb

View 7mfb on RCSB PDB site
Description: Crystal structure of antibody 10E8v4 Fab - light chain H31F variant
Class: immune system
Keywords: Monoclonal antibody 10E8, MPER, cis-trans isomerization, size-exclusion chromatography, IMMUNE SYSTEM
Deposited on 2021-04-08, released 2021-07-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-14, with a file datestamp of 2021-07-09.
Experiment type: XRAY
Resolution: 1.74 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Antibody 10E8v4 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Gene: IGHV3-15*05
    Database cross-references and differences (RAF-indexed):
    • PDB 7MFB (0-231)
    Domains in SCOPe 2.08: d7mfbh_
  • Chain 'L':
    Compound: Antibody 10E8v4 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Gene: IGLV3-19*01
    Database cross-references and differences (RAF-indexed):
    • PDB 7MFB (0-209)
    Domains in SCOPe 2.08: d7mfbl1, d7mfbl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7mfbH (H:)
evrlvesggglvkpggslrlscsasgfdfdnawmtwvrqppgkglewvgritgpgegwsv
dyaesvkgrftisrdntkntlylemnnvrtedtgyyfcartgkyydfwsgyppgeeyfqd
wgqgtlvivssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsg
vhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7mfbL (L:)
seltqdpavsvalkqtvtitcrgdslrsfyaswyqkkpgqapvllfygknnrpsgipdrf
sgsasgnrasltitgaqaedeadyycssrdksgsrlsvfgggtkltvlsqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvap