PDB entry 7mea

View 7mea on RCSB PDB site
Description: CDD-1 beta-lactamase in imidazole/MPD 1 minute avibactam complex
Class: hydrolase/inhibitor
Keywords: Gram-positive, beta-lactamase, antibiotic resistance, inhibitor, avibactam, HYDROLASE, HYDROLASE-INHIBITOR complex
Deposited on 2021-04-06, released 2022-02-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-02-16, with a file datestamp of 2022-02-11.
Experiment type: XRAY
Resolution: 1.73 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Beta-lactamase
  Species: Clostridioides difficile [TaxId:1496]
  Gene: blaR1_1, E5F32_07085, E5F39_11445, SAMEA3374989_01677
  Database cross-references and differences (RAF-indexed):
  • Uniprot A0A160YKM3 (0-249)
    • engineered mutation (178)
    • engineered mutation (184)
  Domains in SCOPe 2.08: d7meaa_
• Heterogens: NXL, SO4, MPD, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >7meaA (A:)
  vnivdysdcfegisggaifcntknkeyniynkelietrrspcstfkivstliglekgvin
  skesvmgydgtdypnknwnknlsleeafkescvwyykklinkvdaksvqnilddlkygnc
  disewegdlkngkghlngfwlesslqispkeqvqtmakifegdtnfkkehinilrdimai
  dvndaninvygktgtgfdeknkrvdawfvgmleregdtyyfaiksddsnkeitgpkvkei
  ainiikkyys