PDB entry 7mbq

View 7mbq on RCSB PDB site
Description: cryo-em structure of zebrafish trpm5 in the presence of 5 mm calcium
Deposited on 2021-04-01, released 2021-07-07
The last revision was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: EM
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transient receptor potential melastatin 5
    Species: Danio rerio [TaxId:7955]
    Gene: trpm5, TRPM5
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Transient receptor potential melastatin 5
    Species: Danio rerio [TaxId:7955]
    Gene: trpm5, TRPM5
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Transient receptor potential melastatin 5
    Species: Danio rerio [TaxId:7955]
    Gene: trpm5, TRPM5
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Transient receptor potential melastatin 5
    Species: Danio rerio [TaxId:7955]
    Gene: trpm5, TRPM5
    Database cross-references and differences (RAF-indexed):
  • Heterogens: CA, YUV, YUY, NAG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7mbqA (A:)
mveksserfdkqmagrlgdidftgvsrtrgkfvrvtsstdpaeiyqiltkqwglapphlv
valmggdevaqlkpwlrdtlrkglvkaaqstgawiltsglrfgitknlgqavrdhslast
spkvrvvaigiapwnmiqnrdlllsakpdhpatyptedlpygavysldcnhshfilvded
pkrpgatgemrvkmlkhislqrtgyggtgsieipvlcllvhgeprilqkmykniqnsipw
lilagsggvadilvtlmdrgcwdadivqellintfpdglhsteitswtkliqrildhghl
ltvhdpeqdseldtvilkalvkacksqsqeaqdfldelklavawnrvdiakseifsgdvq
wsaqdleevmmealvndkpdfvrlfvdngvnikqfltygrlqelycsvseknllhtlllk
knqerqaqlarkrmsgnpnnelgdrkfrftfhevskvlkdflddtckgfyqklpaermgk
grlfhsqknlpdmdrrcehpwrdlflwailqnrqemanyfwamgpeavaaalvgckimke
mahlateaesarsmknakyeqfamdlfsecysnsedraysllvrktccwskatvlniatl
aeakcffahdgvqalltkvwwgamrtdtsisrlvltffipplvwtslikfnpeeqvskde
gepfaeldsleteqallltdgdpvagegsaetaarscsatfirvvlrrwnrfwsapvtvf
mgnvimyfaflilfsyvllldfrppppygpsaaeiilyfwvftlvleeirqsfftdedms
ilkkmklyvednwnkcdmvaislfvvglscrmamstyeagrtvlaldfmvftlrlihifa
ihkqlgpkiiivermikdvffflfflsvwliaygvttqallhpndpridwvfrralyrpy
lhifgqipleeidaakmpddncttdvqeiilgtlppcpniyanwlvilllviyllvtnvl
llnlliamfsytfqvvqenadifwkfqrynliveyhsrpalappfiiishitqallsfik
ktentqdllerelpsgldqklmtwetvqkenylaklehehressgerlrytsskvqtllr
mvggfkdqekrmatvetevrycgevlswiaecfhkstlkcdrdapkaprsiagssrdqqp
qgakrqqpgghpaygtdkklpfidh

    Sequence, based on observed residues (ATOM records):
    >7mbqA (A:)
rlgdidftgvsrtrgkfvrvtsstdpaeiyqiltkqwglapphlvvalmggdevaqlkpw
lrdtlrkglvkaaqstgawiltsglrfgitknlgqavrdhslastspkvrvvaigiapwn
miqnrdlllsakpdhpatyptedlpygavysldcnhshfilvdedpkrpgatgemrvkml
khislqrtgyggtgsieipvlcllvhgeprilqkmykniqnsipwlilagsggvadilvt
lmdrgcwdadivqellintfpdglhsteitswtkliqrildhghlltvhdpeqdseldtv
ilkalvkacksqsqeaqdfldelklavawnrvdiakseifsgdvqwsaqdleevmmealv
ndkpdfvrlfvdngvnikqfltygrlqelycsvseknllhtlllkknqerqaqlkfrftf
hevskvlkdflddtckgfyqklnlpdmdrrcehpwrdlflwailqnrqemanyfwamgpe
avaaalvgckimkemahlateaesarsmknakyeqfamdlfsecysnsedraysllvrkt
ccwskatvlniatlaeakcffahdgvqalltkvwwgamrtdtsisrlvltffipplvwts
likfnpesatfirvvlrrwnrfwsapvtvfmgnvimyfaflilfsyvllldfrppppygp
saaeiilyfwvftlvleeirqsfftdedmsilkkmklyvednwnkcdmvaislfvvglsc
rmamstyeagrtvlaldfmvftlrlihifaihkqlgpkiiivermikdvffflfflsvwl
iaygvttqallhpndpridwvfrralyrpylhifgqipleeidaakmpddncttdvqeii
lgtlppcpniyanwlvilllviyllvtnvlllnlliamfsytfqvvqenadifwkfqryn
liveyhsrpalappfiiishitqallsfikdllerelpsgldqklmtwetvqkenylakl
ehehressgerlrytsskvqtllrmvggfkdqekrm

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7mbqB (B:)
mveksserfdkqmagrlgdidftgvsrtrgkfvrvtsstdpaeiyqiltkqwglapphlv
valmggdevaqlkpwlrdtlrkglvkaaqstgawiltsglrfgitknlgqavrdhslast
spkvrvvaigiapwnmiqnrdlllsakpdhpatyptedlpygavysldcnhshfilvded
pkrpgatgemrvkmlkhislqrtgyggtgsieipvlcllvhgeprilqkmykniqnsipw
lilagsggvadilvtlmdrgcwdadivqellintfpdglhsteitswtkliqrildhghl
ltvhdpeqdseldtvilkalvkacksqsqeaqdfldelklavawnrvdiakseifsgdvq
wsaqdleevmmealvndkpdfvrlfvdngvnikqfltygrlqelycsvseknllhtlllk
knqerqaqlarkrmsgnpnnelgdrkfrftfhevskvlkdflddtckgfyqklpaermgk
grlfhsqknlpdmdrrcehpwrdlflwailqnrqemanyfwamgpeavaaalvgckimke
mahlateaesarsmknakyeqfamdlfsecysnsedraysllvrktccwskatvlniatl
aeakcffahdgvqalltkvwwgamrtdtsisrlvltffipplvwtslikfnpeeqvskde
gepfaeldsleteqallltdgdpvagegsaetaarscsatfirvvlrrwnrfwsapvtvf
mgnvimyfaflilfsyvllldfrppppygpsaaeiilyfwvftlvleeirqsfftdedms
ilkkmklyvednwnkcdmvaislfvvglscrmamstyeagrtvlaldfmvftlrlihifa
ihkqlgpkiiivermikdvffflfflsvwliaygvttqallhpndpridwvfrralyrpy
lhifgqipleeidaakmpddncttdvqeiilgtlppcpniyanwlvilllviyllvtnvl
llnlliamfsytfqvvqenadifwkfqrynliveyhsrpalappfiiishitqallsfik
ktentqdllerelpsgldqklmtwetvqkenylaklehehressgerlrytsskvqtllr
mvggfkdqekrmatvetevrycgevlswiaecfhkstlkcdrdapkaprsiagssrdqqp
qgakrqqpgghpaygtdkklpfidh

    Sequence, based on observed residues (ATOM records):
    >7mbqB (B:)
rlgdidftgvsrtrgkfvrvtsstdpaeiyqiltkqwglapphlvvalmggdevaqlkpw
lrdtlrkglvkaaqstgawiltsglrfgitknlgqavrdhslastspkvrvvaigiapwn
miqnrdlllsakpdhpatyptedlpygavysldcnhshfilvdedpkrpgatgemrvkml
khislqrtgyggtgsieipvlcllvhgeprilqkmykniqnsipwlilagsggvadilvt
lmdrgcwdadivqellintfpdglhsteitswtkliqrildhghlltvhdpeqdseldtv
ilkalvkacksqsqeaqdfldelklavawnrvdiakseifsgdvqwsaqdleevmmealv
ndkpdfvrlfvdngvnikqfltygrlqelycsvseknllhtlllkknqerqaqlkfrftf
hevskvlkdflddtckgfyqklnlpdmdrrcehpwrdlflwailqnrqemanyfwamgpe
avaaalvgckimkemahlateaesarsmknakyeqfamdlfsecysnsedraysllvrkt
ccwskatvlniatlaeakcffahdgvqalltkvwwgamrtdtsisrlvltffipplvwts
likfnpesatfirvvlrrwnrfwsapvtvfmgnvimyfaflilfsyvllldfrppppygp
saaeiilyfwvftlvleeirqsfftdedmsilkkmklyvednwnkcdmvaislfvvglsc
rmamstyeagrtvlaldfmvftlrlihifaihkqlgpkiiivermikdvffflfflsvwl
iaygvttqallhpndpridwvfrralyrpylhifgqipleeidaakmpddncttdvqeii
lgtlppcpniyanwlvilllviyllvtnvlllnlliamfsytfqvvqenadifwkfqryn
liveyhsrpalappfiiishitqallsfikdllerelpsgldqklmtwetvqkenylakl
ehehressgerlrytsskvqtllrmvggfkdqekrm

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7mbqC (C:)
mveksserfdkqmagrlgdidftgvsrtrgkfvrvtsstdpaeiyqiltkqwglapphlv
valmggdevaqlkpwlrdtlrkglvkaaqstgawiltsglrfgitknlgqavrdhslast
spkvrvvaigiapwnmiqnrdlllsakpdhpatyptedlpygavysldcnhshfilvded
pkrpgatgemrvkmlkhislqrtgyggtgsieipvlcllvhgeprilqkmykniqnsipw
lilagsggvadilvtlmdrgcwdadivqellintfpdglhsteitswtkliqrildhghl
ltvhdpeqdseldtvilkalvkacksqsqeaqdfldelklavawnrvdiakseifsgdvq
wsaqdleevmmealvndkpdfvrlfvdngvnikqfltygrlqelycsvseknllhtlllk
knqerqaqlarkrmsgnpnnelgdrkfrftfhevskvlkdflddtckgfyqklpaermgk
grlfhsqknlpdmdrrcehpwrdlflwailqnrqemanyfwamgpeavaaalvgckimke
mahlateaesarsmknakyeqfamdlfsecysnsedraysllvrktccwskatvlniatl
aeakcffahdgvqalltkvwwgamrtdtsisrlvltffipplvwtslikfnpeeqvskde
gepfaeldsleteqallltdgdpvagegsaetaarscsatfirvvlrrwnrfwsapvtvf
mgnvimyfaflilfsyvllldfrppppygpsaaeiilyfwvftlvleeirqsfftdedms
ilkkmklyvednwnkcdmvaislfvvglscrmamstyeagrtvlaldfmvftlrlihifa
ihkqlgpkiiivermikdvffflfflsvwliaygvttqallhpndpridwvfrralyrpy
lhifgqipleeidaakmpddncttdvqeiilgtlppcpniyanwlvilllviyllvtnvl
llnlliamfsytfqvvqenadifwkfqrynliveyhsrpalappfiiishitqallsfik
ktentqdllerelpsgldqklmtwetvqkenylaklehehressgerlrytsskvqtllr
mvggfkdqekrmatvetevrycgevlswiaecfhkstlkcdrdapkaprsiagssrdqqp
qgakrqqpgghpaygtdkklpfidh

    Sequence, based on observed residues (ATOM records):
    >7mbqC (C:)
rlgdidftgvsrtrgkfvrvtsstdpaeiyqiltkqwglapphlvvalmggdevaqlkpw
lrdtlrkglvkaaqstgawiltsglrfgitknlgqavrdhslastspkvrvvaigiapwn
miqnrdlllsakpdhpatyptedlpygavysldcnhshfilvdedpkrpgatgemrvkml
khislqrtgyggtgsieipvlcllvhgeprilqkmykniqnsipwlilagsggvadilvt
lmdrgcwdadivqellintfpdglhsteitswtkliqrildhghlltvhdpeqdseldtv
ilkalvkacksqsqeaqdfldelklavawnrvdiakseifsgdvqwsaqdleevmmealv
ndkpdfvrlfvdngvnikqfltygrlqelycsvseknllhtlllkknqerqaqlkfrftf
hevskvlkdflddtckgfyqklnlpdmdrrcehpwrdlflwailqnrqemanyfwamgpe
avaaalvgckimkemahlateaesarsmknakyeqfamdlfsecysnsedraysllvrkt
ccwskatvlniatlaeakcffahdgvqalltkvwwgamrtdtsisrlvltffipplvwts
likfnpesatfirvvlrrwnrfwsapvtvfmgnvimyfaflilfsyvllldfrppppygp
saaeiilyfwvftlvleeirqsfftdedmsilkkmklyvednwnkcdmvaislfvvglsc
rmamstyeagrtvlaldfmvftlrlihifaihkqlgpkiiivermikdvffflfflsvwl
iaygvttqallhpndpridwvfrralyrpylhifgqipleeidaakmpddncttdvqeii
lgtlppcpniyanwlvilllviyllvtnvlllnlliamfsytfqvvqenadifwkfqryn
liveyhsrpalappfiiishitqallsfikdllerelpsgldqklmtwetvqkenylakl
ehehressgerlrytsskvqtllrmvggfkdqekrm

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7mbqD (D:)
mveksserfdkqmagrlgdidftgvsrtrgkfvrvtsstdpaeiyqiltkqwglapphlv
valmggdevaqlkpwlrdtlrkglvkaaqstgawiltsglrfgitknlgqavrdhslast
spkvrvvaigiapwnmiqnrdlllsakpdhpatyptedlpygavysldcnhshfilvded
pkrpgatgemrvkmlkhislqrtgyggtgsieipvlcllvhgeprilqkmykniqnsipw
lilagsggvadilvtlmdrgcwdadivqellintfpdglhsteitswtkliqrildhghl
ltvhdpeqdseldtvilkalvkacksqsqeaqdfldelklavawnrvdiakseifsgdvq
wsaqdleevmmealvndkpdfvrlfvdngvnikqfltygrlqelycsvseknllhtlllk
knqerqaqlarkrmsgnpnnelgdrkfrftfhevskvlkdflddtckgfyqklpaermgk
grlfhsqknlpdmdrrcehpwrdlflwailqnrqemanyfwamgpeavaaalvgckimke
mahlateaesarsmknakyeqfamdlfsecysnsedraysllvrktccwskatvlniatl
aeakcffahdgvqalltkvwwgamrtdtsisrlvltffipplvwtslikfnpeeqvskde
gepfaeldsleteqallltdgdpvagegsaetaarscsatfirvvlrrwnrfwsapvtvf
mgnvimyfaflilfsyvllldfrppppygpsaaeiilyfwvftlvleeirqsfftdedms
ilkkmklyvednwnkcdmvaislfvvglscrmamstyeagrtvlaldfmvftlrlihifa
ihkqlgpkiiivermikdvffflfflsvwliaygvttqallhpndpridwvfrralyrpy
lhifgqipleeidaakmpddncttdvqeiilgtlppcpniyanwlvilllviyllvtnvl
llnlliamfsytfqvvqenadifwkfqrynliveyhsrpalappfiiishitqallsfik
ktentqdllerelpsgldqklmtwetvqkenylaklehehressgerlrytsskvqtllr
mvggfkdqekrmatvetevrycgevlswiaecfhkstlkcdrdapkaprsiagssrdqqp
qgakrqqpgghpaygtdkklpfidh

    Sequence, based on observed residues (ATOM records):
    >7mbqD (D:)
rlgdidftgvsrtrgkfvrvtsstdpaeiyqiltkqwglapphlvvalmggdevaqlkpw
lrdtlrkglvkaaqstgawiltsglrfgitknlgqavrdhslastspkvrvvaigiapwn
miqnrdlllsakpdhpatyptedlpygavysldcnhshfilvdedpkrpgatgemrvkml
khislqrtgyggtgsieipvlcllvhgeprilqkmykniqnsipwlilagsggvadilvt
lmdrgcwdadivqellintfpdglhsteitswtkliqrildhghlltvhdpeqdseldtv
ilkalvkacksqsqeaqdfldelklavawnrvdiakseifsgdvqwsaqdleevmmealv
ndkpdfvrlfvdngvnikqfltygrlqelycsvseknllhtlllkknqerqaqlkfrftf
hevskvlkdflddtckgfyqklnlpdmdrrcehpwrdlflwailqnrqemanyfwamgpe
avaaalvgckimkemahlateaesarsmknakyeqfamdlfsecysnsedraysllvrkt
ccwskatvlniatlaeakcffahdgvqalltkvwwgamrtdtsisrlvltffipplvwts
likfnpesatfirvvlrrwnrfwsapvtvfmgnvimyfaflilfsyvllldfrppppygp
saaeiilyfwvftlvleeirqsfftdedmsilkkmklyvednwnkcdmvaislfvvglsc
rmamstyeagrtvlaldfmvftlrlihifaihkqlgpkiiivermikdvffflfflsvwl
iaygvttqallhpndpridwvfrralyrpylhifgqipleeidaakmpddncttdvqeii
lgtlppcpniyanwlvilllviyllvtnvlllnlliamfsytfqvvqenadifwkfqryn
liveyhsrpalappfiiishitqallsfikdllerelpsgldqklmtwetvqkenylakl
ehehressgerlrytsskvqtllrmvggfkdqekrm