PDB entry 7mah

View 7mah on RCSB PDB site
Description: HIV-1 Protease (I84V) in Complex with PU4 (LR2-78)
Class: hydrolase/hydrolase inhibitor
Keywords: hiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex
Deposited on 2021-03-31, released 2022-04-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-04-27, with a file datestamp of 2022-04-22.
Experiment type: XRAY
Resolution: 1.88 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Protease
  Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • conflict (6)
    • conflict (36)
    • engineered mutation (83)
  Domains in SCOPe 2.08: d7maha_
• Chain 'B':
  Compound: Protease
  Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • conflict (6)
    • conflict (36)
    • engineered mutation (83)
  Domains in SCOPe 2.08: d7mahb_
• Heterogens: XVM, SO4, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >7mahA (A:)
  pqitlwkrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvnvigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >7mahB (B:)
  pqitlwkrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvnvigrnlltqigctlnf