PDB entry 7m9n

View 7m9n on RCSB PDB site
Description: HIV-1 Protease (I84V) in Complex with LR3-68
Class: hydrolase/hydrolase inhibitor
Keywords: HIV, NL4-3 PROTEASE, DRUG RESISTANCE, PROTEASE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2021-03-31, released 2022-04-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-04-20, with a file datestamp of 2022-04-15.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Protease
  Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • conflict (6)
    • conflict (36)
    • engineered mutation (83)
  Domains in SCOPe 2.08: d7m9na_
• Chain 'B':
  Compound: Protease
  Species: HUMAN IMMUNODEFICIENCY VIRUS 1 [TaxId:11676]
  Gene: gag-pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • conflict (6)
    • conflict (36)
    • engineered mutation (83)
  Domains in SCOPe 2.08: d7m9nb_
• Heterogens: YWM, SO4, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >7m9nA (A:)
  pqitlwkrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvnvigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >7m9nB (B:)
  pqitlwkrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvnvigrnlltqigctlnf