PDB entry 7m6h

View 7m6h on RCSB PDB site
Description: structure of the sars-cov-2 s 2p trimer in complex with the human neutralizing antibody fab fragment, bg7-20
Deposited on 2021-03-25, released 2021-05-05
The last revision was dated 2021-06-23, with a file datestamp of 2021-06-18.
Experiment type: EM
Resolution: 4 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (985-986)
  • Chain 'B':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (985-986)
  • Chain 'C':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (985-986)
  • Chain 'D':
    Compound: BG7-20 Fab Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7M6H (0-End)
  • Chain 'E':
    Compound: BG7-20 Fab Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7M6H (0-End)
  • Chain 'F':
    Compound: BG7-20 Fab Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7M6H
  • Chain 'G':
    Compound: BG7-20 Fab Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7M6H
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7m6hA (A:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqyikwpsgrlvprgspgsgyipeaprdgqayvrkdgewvllstflghhhhhh

    Sequence, based on observed residues (ATOM records):
    >7m6hA (A:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihdnpvlpfndgvyfaste
ksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvnctfeyvsfknlr
efvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhaayyv
gylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesiv
rfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkl
ndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvgg
nynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqp
yrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgr
diadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevnvfqtra
gcligaehvnnsyecdipigagicasyqtsqsiiaytmslgaensvaysnnsiaiptnft
isvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntq
evfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtkfngltvlppll
tdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklian
qfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrld
ppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgk
gyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvt
qrnfyepqiittdntfvsgncdvvigivnntvydplqpelds

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7m6hB (B:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqyikwpsgrlvprgspgsgyipeaprdgqayvrkdgewvllstflghhhhhh

    Sequence, based on observed residues (ATOM records):
    >7m6hB (B:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihdnpvlpfndgvyfaste
ksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvnctfeyvsfknlr
efvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhaayyv
gylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesiv
rfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkl
ndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvgg
nynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqp
yrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgr
diadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevnvfqtra
gcligaehvnnsyecdipigagicasyqtsqsiiaytmslgaensvaysnnsiaiptnft
isvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntq
evfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtkfngltvlppll
tdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklian
qfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrld
ppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgk
gyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvt
qrnfyepqiittdntfvsgncdvvigivnntvydplqpelds

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7m6hC (C:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqslliv
nnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdle
gkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqt
llalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetk
ctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisn
cvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiad
ynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpc
ngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvn
fnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp
gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsy
ecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnfti
svtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqe
vfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdc
lgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam
qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqaln
tlvkqlssnfgaissvlndilsrldppeaevqidrlitgrlqslqtyvtqqliraaeira
sanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapa
ichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp
lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidl
qelgkyeqyikwpsgrlvprgspgsgyipeaprdgqayvrkdgewvllstflghhhhhh

    Sequence, based on observed residues (ATOM records):
    >7m6hC (C:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihdnpvlpfndgvyfaste
ksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvnctfeyvsfknlr
efvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhaayyv
gylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesiv
rfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkl
ndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvgg
nynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqp
yrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgr
diadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevnvfqtra
gcligaehvnnsyecdipigagicasyqtsqsiiaytmslgaensvaysnnsiaiptnft
isvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntq
evfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtkfngltvlppll
tdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklian
qfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrld
ppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgk
gyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvt
qrnfyepqiittdntfvsgncdvvigivnntvydplqpelds

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7m6hD (D:)
qvqlvqsgaevkkagasvkvsckasgytftsydinwvrqasgqglewmgwmnpisgntgy
aqkfqgrvtmtrntsittaymelsslrsedtavyfcarggrycssttcysgvgmdvwgqg
ttvtvpsastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtf
pavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkt

    Sequence, based on observed residues (ATOM records):
    >7m6hD (D:)
qvqlvqsgaevkkagasvkvsckasgytftsydinwvrqasgqglewmgwmnpisgntgy
aqkfqgrvtmtrntsittaymelsslrsedtavyfcarggrycssttcysgvgmdvwgqg
ttvtvp

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7m6hE (E:)
qvqlvqsgaevkkagasvkvsckasgytftsydinwvrqasgqglewmgwmnpisgntgy
aqkfqgrvtmtrntsittaymelsslrsedtavyfcarggrycssttcysgvgmdvwgqg
ttvtvpsastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtf
pavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkt

    Sequence, based on observed residues (ATOM records):
    >7m6hE (E:)
qvqlvqsgaevkkagasvkvsckasgytftsydinwvrqasgqglewmgwmnpisgntgy
aqkfqgrvtmtrntsittaymelsslrsedtavyfcarggrycssttcysgvgmdvwgqg
ttvtvp

  • Chain 'F':
    Sequence, based on SEQRES records:
    >7m6hF (F:)
qsvltqppsvsgapgqrvtisctgsssnigagydvhwyhqlpgtapkfliygnsnrpsgv
pdrfsgsksgtsaslaitrlqaedeadyycqsydsslsgwvfgggtkltvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records):
    >7m6hF (F:)
vltqppsvsgapgqrvtisctgsssnigagydvhwyhqlpgtapkfliygnsnrpsgvpd
rfsgsksgtsaslaitrlqaedeadyycqsydsslsgwvfgggtkltvl

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7m6hG (G:)
qsvltqppsvsgapgqrvtisctgsssnigagydvhwyhqlpgtapkfliygnsnrpsgv
pdrfsgsksgtsaslaitrlqaedeadyycqsydsslsgwvfgggtkltvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records):
    >7m6hG (G:)
vltqppsvsgapgqrvtisctgsssnigagydvhwyhqlpgtapkfliygnsnrpsgvpd
rfsgsksgtsaslaitrlqaedeadyycqsydsslsgwvfgggtkltvl