PDB entry 7m6d

View 7m6d on RCSB PDB site
Description: Structure of the SARS-CoV-2 RBD in complex with neutralizing antibodies BG4-25 and CR3022
Class: viral protein/antiviral protein
Keywords: SARS-CoV-2, Coronavirus, COVID-19, antibody, neutralizing antibody, receptor binding domain, spike glycoprotein, ANTIVIRAL PROTEIN, VIRAL PROTEIN-ANTIVIRAL PROTEIN complex
Deposited on 2021-03-25, released 2021-05-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-23, with a file datestamp of 2021-06-18.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: CR3022 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7M6D (0-End)
    Domains in SCOPe 2.08: d7m6da_
  • Chain 'B':
    Compound: CR3022 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7M6D (0-220)
    Domains in SCOPe 2.08: d7m6db1, d7m6db2
  • Chain 'C':
    Compound: Spike protein S1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7m6dc_
  • Chain 'H':
    Compound: BG4-25 Fab Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7M6D (0-End)
    Domains in SCOPe 2.08: d7m6dh_
  • Chain 'L':
    Compound: BG4-25 Fab Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7M6D (0-214)
    Domains in SCOPe 2.08: d7m6dl1, d7m6dl2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7m6dA (A:)
qmqlvqsgtevkkpgeslkisckgsgygfitywigwvrqmpgkglewmgiiypgdsetry
spsfqgqvtisadksintaylqwsslkasdtaiyycaggsgistpmdvwgqgttvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkt

    Sequence, based on observed residues (ATOM records): (download) 
    >7m6dA (A:)
qmqlvqsgtevkkpgeslkisckgsgygfitywigwvrqmpgkglewmgiiypgdsetry
spsfqgqvtisadksintaylqwsslkasdtaiyycaggsgistpmdvwgqgttvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7m6dB (B:)
diqltqspdslavslgeratinckssqsvlyssinknylawyqqkpgqppklliywastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyystpytfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgecs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7m6dC (C:)
rfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkl
ndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvgg
nynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqp
yrvvvlsfellhapatvcgpkkstnlhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7m6dC (C:)
tnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcf
tnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynyl
yrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrvvv
lsfellhapatvcgpk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >7m6dH (H:)
evqlvesgggliqpggslrlscaasgitvvrnymtwvrqapgkglewvsviysggttyya
dsvkgrftisrdnskntmylqmnslraedtaiyycardlevvgamdvwgqgttvtvssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkt

    Sequence, based on observed residues (ATOM records): (download) 
    >7m6dH (H:)
evqlvesgggliqpggslrlscaasgitvvrnymtwvrqapgkglewvsviysggttyya
dsvkgrftisrdnskntmylqmnslraedtaiyycardlevvgamdvwgqgttvtvssas
tkgpsvfplapsstaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssslgtqtyicnvnhkpsntkvdkrvepks

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7m6dL (L:)
eivltqspgtlslspgeratlscrasqsvpssylawyqqkpgqaprlliygassratgip
drfsgsgsgtdftltisrlepedfavyycqqygspmytfgqgtkleikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec