PDB entry 7m2f

View 7m2f on RCSB PDB site
Description: CDK2 with compound 14 inhibitor with carboxylate
Class: SIGNALING PROTEIN, Transferase/Inhibitor
Keywords: CDK2, CDK9, kinase inhibitor, SIGNALING PROTEIN, Transferase-Inhibitor complex
Deposited on 2021-03-16, released 2021-07-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: XRAY
Resolution: 1.63 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7m2fa_
  • Heterogens: YOS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >7m2fA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >7m2fA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkistaireisllkelnhpnivklldvi
    htenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlkp
    qnllintegaikladfgpvrtythevvtlwyrapeillgckyystavdiwslgcifaemv
    trralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvpplde
    dgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl