PDB entry 7m01

View 7m01 on RCSB PDB site
Description: Structure of SARS-CoV-2 3CL protease in complex with inhibitor 14c
Class: hydrolase/inhibitor
Keywords: COVID-19, PROTEASE, severe acute respiratory syndrome coronavirus 2, SARS-CoV-2 3CL protease Inhhibitors, HYDROLASE-INHIBITOR complex
Deposited on 2021-03-10, released 2021-03-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-24, with a file datestamp of 2021-03-19.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C-like proteinase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7m01a_
  • Chain 'B':
    Compound: 3C-like proteinase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7m01b_
  • Heterogens: YKV, YKS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7m01A (A:)
snigsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyed
llirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvla
cyngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtd
legnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamk
ynyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdv
vrqcsgvtf

    Sequence, based on observed residues (ATOM records): (download) 
    >7m01A (A:)
rkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllirksn
hnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyngsps
gvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegnfyg
pfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynyeplt
qdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7m01B (B:)
snigsgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyed
llirksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvla
cyngspsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtd
legnfygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamk
ynyepltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdv
vrqcsgvtf

    Sequence, based on observed residues (ATOM records): (download) 
    >7m01B (B:)
frkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllirks
nhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyngsp
sgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegnfy
gpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynyepl
tqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqcs