PDB entry 7lzs

View 7lzs on RCSB PDB site
Description: Crystal structure of the BCL6 BTB domain in complex with OICR-11029
Class: transcription/inhibitor
Keywords: immunity, inflammatory response, transcription repressor, TRANSCRIPTION-INHIBITOR complex
Deposited on 2021-03-10, released 2022-03-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-03-16, with a file datestamp of 2022-03-11.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41182 (0-124)
      • engineered mutation (3)
      • engineered mutation (62)
      • engineered mutation (79)
    Domains in SCOPe 2.08: d7lzsa_
  • Heterogens: YJS, DMS, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7lzsA (A:)
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lkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkf
ikase

    Sequence, based on observed residues (ATOM records): (download) 
    >7lzsA (A:)
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rnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkfik
as