SCOPe 2.08: Structural Classification of Proteins

PDB entry 7lws

View 7lws on RCSB PDB site
Description: uk (b.1.1.7) sars-cov-2 s-gsas-d614g variant spike protein in the 3- rbd-down conformation
Deposited on 2021-03-01, released 2021-03-31
The last revision was dated 2021-06-30, with a file datestamp of 2021-06-25.
Experiment type: EM
Resolution: 3.22 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Spike glycoprotein
Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
Gene: S, 2
Database cross-references and differences (RAF-indexed):
- Uniprot P0DTC2
  - engineered mutation (497)
  - engineered mutation (566)
  - engineered mutation (610)
  - engineered mutation (712)
  - engineered mutation (978)
  - engineered mutation (1114)
Chain 'B':
Compound: Spike glycoprotein
Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
Gene: S, 2
Database cross-references and differences (RAF-indexed):
- Uniprot P0DTC2
  - engineered mutation (497)
  - engineered mutation (566)
  - engineered mutation (610)
  - engineered mutation (712)
  - engineered mutation (978)
  - engineered mutation (1114)
Chain 'C':
Compound: Spike glycoprotein
Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
Gene: S, 2
Database cross-references and differences (RAF-indexed):
- Uniprot P0DTC2
  - engineered mutation (497)
  - engineered mutation (566)
  - engineered mutation (610)
  - engineered mutation (712)
  - engineered mutation (978)
  - engineered mutation (1114)
Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

Chain 'A':
Sequence, based on SEQRES records:

>7lwsA (A:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaisgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqsllivnn
atnvvikvcefqfcndpflgvyhknnkswmesefrvyssannctfeyvsqpflmdlegkq
gnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtlla
lhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctl
ksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncva
dysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadyny
klpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngv
egfncyfplqsygfqptygvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnf
ngltgtgvltesnkkflpfqqfgrdiddttdavrdpqtleilditpcsfggvsvitpgtn
tsnqvavlyqgvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecd
ipigagicasyqtqtnshgsassvasqsiiaytmslgaensvaysnnsiaipinftisvt
teilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfa
qvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdclgd
iaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqma
yrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlv
kqlssnfgaissvlndilarldkveaevqidrlitgrlqslqtyvtqqliraaeirasan
laatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaich
dgkahfpregvfvsngthwfvtqrnfyepqiitthntfvsgncdvvigivnntvydplqp
eldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqel
gkyeqgsgyipeaprdgqayvrkdgewvllstflgrslevlfqgpghhhhhhhhsawshp
qfekgggsggggsggsawshpqfek

Sequence, based on observed residues (ATOM records):

>7lwsA (A:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaidnpvlpfndgvyfastek
sniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvnctfeyvsfknlre
fvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhaayyvg
ylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivr
fpninlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklnd
lcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggny
nylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptygvgyqpyr
vvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdi
ddttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqgvnctevnvfqtragc
ligaehvnnsyecdipigagicasyqtsqsiiaytmslgaensvaysnnsiaipinftis
vtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqev
faqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtkfngltvlpplltd
emiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqf
nsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilarldkv
eaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgy
hlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtqr
nfyepqiitthntfvsgncdvvigivnntvydplqpelds

Chain 'B':
Sequence, based on SEQRES records:

>7lwsB (B:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaisgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqsllivnn
atnvvikvcefqfcndpflgvyhknnkswmesefrvyssannctfeyvsqpflmdlegkq
gnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtlla
lhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctl
ksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncva
dysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadyny
klpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngv
egfncyfplqsygfqptygvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnf
ngltgtgvltesnkkflpfqqfgrdiddttdavrdpqtleilditpcsfggvsvitpgtn
tsnqvavlyqgvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecd
ipigagicasyqtqtnshgsassvasqsiiaytmslgaensvaysnnsiaipinftisvt
teilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfa
qvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdclgd
iaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqma
yrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlv
kqlssnfgaissvlndilarldkveaevqidrlitgrlqslqtyvtqqliraaeirasan
laatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaich
dgkahfpregvfvsngthwfvtqrnfyepqiitthntfvsgncdvvigivnntvydplqp
eldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqel
gkyeqgsgyipeaprdgqayvrkdgewvllstflgrslevlfqgpghhhhhhhhsawshp
qfekgggsggggsggsawshpqfek

Sequence, based on observed residues (ATOM records):

>7lwsB (B:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaidnpvlpfndgvyfastek
sniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvnctfeyvsfknlre
fvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhaayyvg
ylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivr
fpninlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklnd
lcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggny
nylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptygvgyqpyr
vvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdi
ddttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqgvnctevnvfqtragc
ligaehvnnsyecdipigagicasyqtsqsiiaytmslgaensvaysnnsiaipinftis
vtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqev
faqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtkfngltvlpplltd
emiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqf
nsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilarldkv
eaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgy
hlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtqr
nfyepqiitthntfvsgncdvvigivnntvydplqpelds

Chain 'C':
Sequence, based on SEQRES records:

>7lwsC (C:)
mfvflvllplvssqcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffs
nvtwfhaisgtngtkrfdnpvlpfndgvyfasteksniirgwifgttldsktqsllivnn
atnvvikvcefqfcndpflgvyhknnkswmesefrvyssannctfeyvsqpflmdlegkq
gnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtlla
lhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctl
ksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncva
dysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadyny
klpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngv
egfncyfplqsygfqptygvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnf
ngltgtgvltesnkkflpfqqfgrdiddttdavrdpqtleilditpcsfggvsvitpgtn
tsnqvavlyqgvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecd
ipigagicasyqtqtnshgsassvasqsiiaytmslgaensvaysnnsiaipinftisvt
teilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfa
qvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdclgd
iaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqma
yrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlv
kqlssnfgaissvlndilarldkveaevqidrlitgrlqslqtyvtqqliraaeirasan
laatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaich
dgkahfpregvfvsngthwfvtqrnfyepqiitthntfvsgncdvvigivnntvydplqp
eldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqel
gkyeqgsgyipeaprdgqayvrkdgewvllstflgrslevlfqgpghhhhhhhhsawshp
qfekgggsggggsggsawshpqfek

Sequence, based on observed residues (ATOM records):

>7lwsC (C:)
aytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaidnpvlpfndgvyfastek
sniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvnctfeyvsfknlre
fvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhaayyvg
ylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivr
fpninlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklnd
lcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggny
nylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptygvgyqpyr
vvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdi
ddttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqgvnctevnvfqtragc
ligaehvnnsyecdipigagicasyqtsqsiiaytmslgaensvaysnnsiaipinftis
vtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqev
faqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtkfngltvlpplltd
emiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqf
nsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilarldkv
eaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgy
hlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtqr
nfyepqiitthntfvsgncdvvigivnntvydplqpelds