PDB entry 7lsf

View 7lsf on RCSB PDB site
Description: Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Western Subtype)
Class: immune system/viral protein
Keywords: Tick-borne encephalitis virus, antibody, EDIII, TBEV, IMMUNE SYSTEM, IMMUNE SYSTEM-VIRAL PROTEIN complex
Deposited on 2021-02-18, released 2021-04-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-04-21, with a file datestamp of 2021-04-16.
Experiment type: XRAY
Resolution: 2.24 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: Envelope protein E
    Species: Tick-borne encephalitis virus (WESTERN SUBTYPE) [TaxId:11088]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7lsfe_
  • Chain 'H':
    Compound: T025 Fab Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LSF (0-End)
    Domains in SCOPe 2.08: d7lsfh_
  • Chain 'L':
    Compound: T025 Fab Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7LSF (0-End)
    Domains in SCOPe 2.08: d7lsfl1, d7lsfl2
  • Heterogens: NA, GOL, HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7lsfE (E:)
mkgltytmcdktkftwkraptdsghdtvvmevtfsgtkpcripvravahgspdvnvamli
tpnptienngggfiemqlppgdniiyvgelshqwfqkgshhhhhhglndifeaqkiewhe

    Sequence, based on observed residues (ATOM records): (download) 
    >7lsfE (E:)
tytmcdktkftwkraptdsghdtvvmevtfsgtkpcripvravahgspdvnvamlitpnp
tienngggfiemqlppgdniiyvgelshqwfqkg

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >7lsfH (H:)
qvqlvesgggvvqpgrslrlscaasgftfsnygmhwvrqapgkgldwvavisydaisksy
adsvegrftisrdnskntlylqmnslraedsavyycaksptaidppfdywgqgtlvtvss
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7lsfH (H:)
qvqlvesgggvvqpgrslrlscaasgftfsnygmhwvrqapgkgldwvavisydaisksy
adsvegrftisrdnskntlylqmnslraedsavyycaksptaidppfdywgqgtlvtvss
astkgpsvfplapssksggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >7lsfL (L:)
eivmtqspatlsvspgeratlscwasqsvssnlawyqqkpgqaprlliygastratgipa
rfsasgsgteftltisslqsedfavyycqqynnwpprfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >7lsfL (L:)
eivmtqspatlsvspgeratlscwasqsvssnlawyqqkpgqaprlliygastratgipa
rfsasgsgteftltisslqsedfavyycqqynnwpprfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge